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An antisense Alu transposon insertion/deletion polymorphism of ALDH1A1 may functionally associate with Parkinson’s disease

BACKGROUND: Aldehyde dehydrogenase 1 (encoded by ALDH1A1) has been shown to protect against Parkinson’s disease (PD) by reducing toxic metabolites of dopamine. We herein revealed an antisense Alu element insertion/deletion polymorphism in intron 4 of ALDH1A1, and hypothesized that it might play a ro...

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Detalles Bibliográficos
Autores principales:	Fan, Hui-Hui, Zheng, Jing, Huang, Xiao-Ya, Wu, Ke-Yun, Cui, Lei, Dong, Hao-Jia, Wang, Zhen, Zhang, Xiong, Zhu, Jian-Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9109383/ https://www.ncbi.nlm.nih.gov/pubmed/35578164 http://dx.doi.org/10.1186/s12877-022-03132-1

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