Tobacco-specific nitrosamine 1-(N-methyl-N-nitrosamino)-1-(3-pyridinyl)-4-butanal (NNA) causes DNA damage and impaired replication/transcription in human lung cells

Thirdhand smoke (THS) is a newly described health hazard composed of toxicants, mutagens and carcinogens, including nicotine-derived tobacco specific nitrosamines (TSNAs), one of which is 1-(N-methyl-N-nitrosamino)-1-(3-pyridinyl)-4-butanal (NNA). Although TSNAs are generally potent carcinogens, the...

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Detalles Bibliográficos
Autores principales: Sarker, Altaf H., Hang, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9109921/
https://www.ncbi.nlm.nih.gov/pubmed/35576221
http://dx.doi.org/10.1371/journal.pone.0267839

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9109921/
https://www.ncbi.nlm.nih.gov/pubmed/35576221
http://dx.doi.org/10.1371/journal.pone.0267839

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