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The protective effects of HIF-1α activation on sepsis induced intestinal mucosal barrier injury in rats model of sepsis
The integrity of the intestinal barrier is critical for protecting the host against the pathogen. The role of hypoxia-inducible factor-1α (HIF-1α) in the intestinal barrier disfunction related to sepsis remained unclear. The purpose of the present study is to investigate the role of HIF-1α on oxidat...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9109928/ https://www.ncbi.nlm.nih.gov/pubmed/35576220 http://dx.doi.org/10.1371/journal.pone.0268445 |