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The protective effects of HIF-1α activation on sepsis induced intestinal mucosal barrier injury in rats model of sepsis

The integrity of the intestinal barrier is critical for protecting the host against the pathogen. The role of hypoxia-inducible factor-1α (HIF-1α) in the intestinal barrier disfunction related to sepsis remained unclear. The purpose of the present study is to investigate the role of HIF-1α on oxidat...

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Detalles Bibliográficos
Autores principales: Lei, Xiuzhen, Teng, Wenbin, Fan, Ying, Zhu, Yeke, Yao, Liuxu, Li, Yuhong, Zhu, Shengmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9109928/
https://www.ncbi.nlm.nih.gov/pubmed/35576220
http://dx.doi.org/10.1371/journal.pone.0268445