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Ulinastatin alleviates early brain injury after intracerebral hemorrhage by inhibiting necroptosis and neuroinflammation via MAPK/NF-κB signaling pathway

PURPOSE: Spontaneous intracerebral hemorrhage (ICH) is a major public health problem with a huge economic burden worldwide. Ulinastatin (UTI), a serine protease inhibitor, has been reported to be anti-inflammatory, immune regulation, and organ protection by reducing reactive oxygen species productio...

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Detalles Bibliográficos
Autores principales:	Wang, Li, Jiao, Wei, Wu, Jiayu, Zhang, Jing, Tang, Min, Chen, Yang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9109988/ https://www.ncbi.nlm.nih.gov/pubmed/35584533 http://dx.doi.org/10.1590/acb370301

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