Cargando…
Data on immunogenicity and reactogenicity to COVID-19 vaccination among patients receiving maintenance dialysis
Compared with the general population, patients receiving maintenance dialysis are at increased risk for morbidity and mortality associated with coronavirus disease 2019 (COVID-19). Currently, data on severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2)-specific immunity post-vaccination...
Autores principales: | , , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9109999/ https://www.ncbi.nlm.nih.gov/pubmed/35600839 http://dx.doi.org/10.1016/j.dib.2022.108271 |
_version_ | 1784709002435756032 |
---|---|
author | Karakizlis, Hristos Nahrgang, Christian Strecker, Kevin Chen, Jiangping Aly, Mostafa Slanina, Heiko Schüttler, Christian G. Esso, Isla Wolter, Martin Todorova, Darina Jessen, Sönke Adamik, Andrea Ronco, Claudio Seeger, Werner Weimer, Rolf Sester, Martina Birk, Horst-Walter Husain-Syed, Faeq |
author_facet | Karakizlis, Hristos Nahrgang, Christian Strecker, Kevin Chen, Jiangping Aly, Mostafa Slanina, Heiko Schüttler, Christian G. Esso, Isla Wolter, Martin Todorova, Darina Jessen, Sönke Adamik, Andrea Ronco, Claudio Seeger, Werner Weimer, Rolf Sester, Martina Birk, Horst-Walter Husain-Syed, Faeq |
author_sort | Karakizlis, Hristos |
collection | PubMed |
description | Compared with the general population, patients receiving maintenance dialysis are at increased risk for morbidity and mortality associated with coronavirus disease 2019 (COVID-19). Currently, data on severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2)-specific immunity post-vaccination in patients on maintenance dialysis are scarce given that the effectiveness of the vaccines has not been explicitly tested in this population due to their common exclusion from SARS-CoV-2 vaccination trials. We herein present data of the specific cellular (interferon-γ and interleukin-2 ELISpot assays) and humoral immune responses (dot plot array and chemiluminescent microparticle immunoassay) at 4 weeks and 6 weeks following a single dose or a complete homologous dual dose SARS-CoV-2 vaccine regimen in 60 adult patients on maintenance dialysis (six with a history of COVID-19). The data was produced in a framework of a project focused on a) quantifying the immune response after full vaccination, b) evaluating the short-term durability of immune response, and c) examining the reactogenicity of SARS-CoV-2 vaccine regimens in patients on maintenance dialysis. |
format | Online Article Text |
id | pubmed-9109999 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-91099992022-05-17 Data on immunogenicity and reactogenicity to COVID-19 vaccination among patients receiving maintenance dialysis Karakizlis, Hristos Nahrgang, Christian Strecker, Kevin Chen, Jiangping Aly, Mostafa Slanina, Heiko Schüttler, Christian G. Esso, Isla Wolter, Martin Todorova, Darina Jessen, Sönke Adamik, Andrea Ronco, Claudio Seeger, Werner Weimer, Rolf Sester, Martina Birk, Horst-Walter Husain-Syed, Faeq Data Brief Data Article Compared with the general population, patients receiving maintenance dialysis are at increased risk for morbidity and mortality associated with coronavirus disease 2019 (COVID-19). Currently, data on severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2)-specific immunity post-vaccination in patients on maintenance dialysis are scarce given that the effectiveness of the vaccines has not been explicitly tested in this population due to their common exclusion from SARS-CoV-2 vaccination trials. We herein present data of the specific cellular (interferon-γ and interleukin-2 ELISpot assays) and humoral immune responses (dot plot array and chemiluminescent microparticle immunoassay) at 4 weeks and 6 weeks following a single dose or a complete homologous dual dose SARS-CoV-2 vaccine regimen in 60 adult patients on maintenance dialysis (six with a history of COVID-19). The data was produced in a framework of a project focused on a) quantifying the immune response after full vaccination, b) evaluating the short-term durability of immune response, and c) examining the reactogenicity of SARS-CoV-2 vaccine regimens in patients on maintenance dialysis. Elsevier 2022-05-16 /pmc/articles/PMC9109999/ /pubmed/35600839 http://dx.doi.org/10.1016/j.dib.2022.108271 Text en © 2022 The Author(s) https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Data Article Karakizlis, Hristos Nahrgang, Christian Strecker, Kevin Chen, Jiangping Aly, Mostafa Slanina, Heiko Schüttler, Christian G. Esso, Isla Wolter, Martin Todorova, Darina Jessen, Sönke Adamik, Andrea Ronco, Claudio Seeger, Werner Weimer, Rolf Sester, Martina Birk, Horst-Walter Husain-Syed, Faeq Data on immunogenicity and reactogenicity to COVID-19 vaccination among patients receiving maintenance dialysis |
title | Data on immunogenicity and reactogenicity to COVID-19 vaccination among patients receiving maintenance dialysis |
title_full | Data on immunogenicity and reactogenicity to COVID-19 vaccination among patients receiving maintenance dialysis |
title_fullStr | Data on immunogenicity and reactogenicity to COVID-19 vaccination among patients receiving maintenance dialysis |
title_full_unstemmed | Data on immunogenicity and reactogenicity to COVID-19 vaccination among patients receiving maintenance dialysis |
title_short | Data on immunogenicity and reactogenicity to COVID-19 vaccination among patients receiving maintenance dialysis |
title_sort | data on immunogenicity and reactogenicity to covid-19 vaccination among patients receiving maintenance dialysis |
topic | Data Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9109999/ https://www.ncbi.nlm.nih.gov/pubmed/35600839 http://dx.doi.org/10.1016/j.dib.2022.108271 |
work_keys_str_mv | AT karakizlishristos dataonimmunogenicityandreactogenicitytocovid19vaccinationamongpatientsreceivingmaintenancedialysis AT nahrgangchristian dataonimmunogenicityandreactogenicitytocovid19vaccinationamongpatientsreceivingmaintenancedialysis AT streckerkevin dataonimmunogenicityandreactogenicitytocovid19vaccinationamongpatientsreceivingmaintenancedialysis AT chenjiangping dataonimmunogenicityandreactogenicitytocovid19vaccinationamongpatientsreceivingmaintenancedialysis AT alymostafa dataonimmunogenicityandreactogenicitytocovid19vaccinationamongpatientsreceivingmaintenancedialysis AT slaninaheiko dataonimmunogenicityandreactogenicitytocovid19vaccinationamongpatientsreceivingmaintenancedialysis AT schuttlerchristiang dataonimmunogenicityandreactogenicitytocovid19vaccinationamongpatientsreceivingmaintenancedialysis AT essoisla dataonimmunogenicityandreactogenicitytocovid19vaccinationamongpatientsreceivingmaintenancedialysis AT woltermartin dataonimmunogenicityandreactogenicitytocovid19vaccinationamongpatientsreceivingmaintenancedialysis AT todorovadarina dataonimmunogenicityandreactogenicitytocovid19vaccinationamongpatientsreceivingmaintenancedialysis AT jessensonke dataonimmunogenicityandreactogenicitytocovid19vaccinationamongpatientsreceivingmaintenancedialysis AT adamikandrea dataonimmunogenicityandreactogenicitytocovid19vaccinationamongpatientsreceivingmaintenancedialysis AT roncoclaudio dataonimmunogenicityandreactogenicitytocovid19vaccinationamongpatientsreceivingmaintenancedialysis AT seegerwerner dataonimmunogenicityandreactogenicitytocovid19vaccinationamongpatientsreceivingmaintenancedialysis AT weimerrolf dataonimmunogenicityandreactogenicitytocovid19vaccinationamongpatientsreceivingmaintenancedialysis AT sestermartina dataonimmunogenicityandreactogenicitytocovid19vaccinationamongpatientsreceivingmaintenancedialysis AT birkhorstwalter dataonimmunogenicityandreactogenicitytocovid19vaccinationamongpatientsreceivingmaintenancedialysis AT husainsyedfaeq dataonimmunogenicityandreactogenicitytocovid19vaccinationamongpatientsreceivingmaintenancedialysis |