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Data on immunogenicity and reactogenicity to COVID-19 vaccination among patients receiving maintenance dialysis

Compared with the general population, patients receiving maintenance dialysis are at increased risk for morbidity and mortality associated with coronavirus disease 2019 (COVID-19). Currently, data on severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2)-specific immunity post-vaccination...

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Autores principales: Karakizlis, Hristos, Nahrgang, Christian, Strecker, Kevin, Chen, Jiangping, Aly, Mostafa, Slanina, Heiko, Schüttler, Christian G., Esso, Isla, Wolter, Martin, Todorova, Darina, Jessen, Sönke, Adamik, Andrea, Ronco, Claudio, Seeger, Werner, Weimer, Rolf, Sester, Martina, Birk, Horst-Walter, Husain-Syed, Faeq
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9109999/
https://www.ncbi.nlm.nih.gov/pubmed/35600839
http://dx.doi.org/10.1016/j.dib.2022.108271
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author Karakizlis, Hristos
Nahrgang, Christian
Strecker, Kevin
Chen, Jiangping
Aly, Mostafa
Slanina, Heiko
Schüttler, Christian G.
Esso, Isla
Wolter, Martin
Todorova, Darina
Jessen, Sönke
Adamik, Andrea
Ronco, Claudio
Seeger, Werner
Weimer, Rolf
Sester, Martina
Birk, Horst-Walter
Husain-Syed, Faeq
author_facet Karakizlis, Hristos
Nahrgang, Christian
Strecker, Kevin
Chen, Jiangping
Aly, Mostafa
Slanina, Heiko
Schüttler, Christian G.
Esso, Isla
Wolter, Martin
Todorova, Darina
Jessen, Sönke
Adamik, Andrea
Ronco, Claudio
Seeger, Werner
Weimer, Rolf
Sester, Martina
Birk, Horst-Walter
Husain-Syed, Faeq
author_sort Karakizlis, Hristos
collection PubMed
description Compared with the general population, patients receiving maintenance dialysis are at increased risk for morbidity and mortality associated with coronavirus disease 2019 (COVID-19). Currently, data on severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2)-specific immunity post-vaccination in patients on maintenance dialysis are scarce given that the effectiveness of the vaccines has not been explicitly tested in this population due to their common exclusion from SARS-CoV-2 vaccination trials. We herein present data of the specific cellular (interferon-γ and interleukin-2 ELISpot assays) and humoral immune responses (dot plot array and chemiluminescent microparticle immunoassay) at 4 weeks and 6 weeks following a single dose or a complete homologous dual dose SARS-CoV-2 vaccine regimen in 60 adult patients on maintenance dialysis (six with a history of COVID-19). The data was produced in a framework of a project focused on a) quantifying the immune response after full vaccination, b) evaluating the short-term durability of immune response, and c) examining the reactogenicity of SARS-CoV-2 vaccine regimens in patients on maintenance dialysis.
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spelling pubmed-91099992022-05-17 Data on immunogenicity and reactogenicity to COVID-19 vaccination among patients receiving maintenance dialysis Karakizlis, Hristos Nahrgang, Christian Strecker, Kevin Chen, Jiangping Aly, Mostafa Slanina, Heiko Schüttler, Christian G. Esso, Isla Wolter, Martin Todorova, Darina Jessen, Sönke Adamik, Andrea Ronco, Claudio Seeger, Werner Weimer, Rolf Sester, Martina Birk, Horst-Walter Husain-Syed, Faeq Data Brief Data Article Compared with the general population, patients receiving maintenance dialysis are at increased risk for morbidity and mortality associated with coronavirus disease 2019 (COVID-19). Currently, data on severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2)-specific immunity post-vaccination in patients on maintenance dialysis are scarce given that the effectiveness of the vaccines has not been explicitly tested in this population due to their common exclusion from SARS-CoV-2 vaccination trials. We herein present data of the specific cellular (interferon-γ and interleukin-2 ELISpot assays) and humoral immune responses (dot plot array and chemiluminescent microparticle immunoassay) at 4 weeks and 6 weeks following a single dose or a complete homologous dual dose SARS-CoV-2 vaccine regimen in 60 adult patients on maintenance dialysis (six with a history of COVID-19). The data was produced in a framework of a project focused on a) quantifying the immune response after full vaccination, b) evaluating the short-term durability of immune response, and c) examining the reactogenicity of SARS-CoV-2 vaccine regimens in patients on maintenance dialysis. Elsevier 2022-05-16 /pmc/articles/PMC9109999/ /pubmed/35600839 http://dx.doi.org/10.1016/j.dib.2022.108271 Text en © 2022 The Author(s) https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Data Article
Karakizlis, Hristos
Nahrgang, Christian
Strecker, Kevin
Chen, Jiangping
Aly, Mostafa
Slanina, Heiko
Schüttler, Christian G.
Esso, Isla
Wolter, Martin
Todorova, Darina
Jessen, Sönke
Adamik, Andrea
Ronco, Claudio
Seeger, Werner
Weimer, Rolf
Sester, Martina
Birk, Horst-Walter
Husain-Syed, Faeq
Data on immunogenicity and reactogenicity to COVID-19 vaccination among patients receiving maintenance dialysis
title Data on immunogenicity and reactogenicity to COVID-19 vaccination among patients receiving maintenance dialysis
title_full Data on immunogenicity and reactogenicity to COVID-19 vaccination among patients receiving maintenance dialysis
title_fullStr Data on immunogenicity and reactogenicity to COVID-19 vaccination among patients receiving maintenance dialysis
title_full_unstemmed Data on immunogenicity and reactogenicity to COVID-19 vaccination among patients receiving maintenance dialysis
title_short Data on immunogenicity and reactogenicity to COVID-19 vaccination among patients receiving maintenance dialysis
title_sort data on immunogenicity and reactogenicity to covid-19 vaccination among patients receiving maintenance dialysis
topic Data Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9109999/
https://www.ncbi.nlm.nih.gov/pubmed/35600839
http://dx.doi.org/10.1016/j.dib.2022.108271
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