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Machine learning sequence prioritization for cell type-specific enhancer design

Recent discoveries of extreme cellular diversity in the brain warrant rapid development of technologies to access specific cell populations within heterogeneous tissue. Available approaches for engineering-targeted technologies for new neuron subtypes are low yield, involving intensive transgenic st...

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Detalles Bibliográficos
Autores principales:	Lawler, Alyssa J, Ramamurthy, Easwaran, Brown, Ashley R, Shin, Naomi, Kim, Yeonju, Toong, Noelle, Kaplow, Irene M, Wirthlin, Morgan, Zhang, Xiaoyu, Phan, BaDoi N, Fox, Grant A, Wade, Kirsten, He, Jing, Ozturk, Bilge Esin, Byrne, Leah C, Stauffer, William R, Fish, Kenneth N, Pfenning, Andreas R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2022
Materias:	Genetics and Genomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9110026/ https://www.ncbi.nlm.nih.gov/pubmed/35576146 http://dx.doi.org/10.7554/eLife.69571

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