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APU-Net: An Attention Mechanism Parallel U-Net for Lung Tumor Segmentation

Lung cancer is one of the malignant tumors with high morbidity and mortality, and lung nodules are the early stages of lung cancer. The symptoms of pulmonary nodules are not obvious in the clinic, and the optimal treatment time is missed due to the missed diagnosis in the clinic. A parallel U-Net ne...

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Autores principales: Zhou, Tao, Dong, YaLi, Lu, HuiLing, Zheng, XiaoMin, Qiu, Shi, Hou, SenBao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9110197/
https://www.ncbi.nlm.nih.gov/pubmed/35586818
http://dx.doi.org/10.1155/2022/5303651
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author Zhou, Tao
Dong, YaLi
Lu, HuiLing
Zheng, XiaoMin
Qiu, Shi
Hou, SenBao
author_facet Zhou, Tao
Dong, YaLi
Lu, HuiLing
Zheng, XiaoMin
Qiu, Shi
Hou, SenBao
author_sort Zhou, Tao
collection PubMed
description Lung cancer is one of the malignant tumors with high morbidity and mortality, and lung nodules are the early stages of lung cancer. The symptoms of pulmonary nodules are not obvious in the clinic, and the optimal treatment time is missed due to the missed diagnosis in the clinic. A parallel U-Net network called APU-Net is proposed. Firstly, two parallel U-Net networks are used to extract the features of different modalities. Among them, the subnetwork UNet_B extracts the CT image features, and the subnetwork UNet_A consists of two encoders to extract the PET/CT and PET image features. Secondly, multimodal feature extraction blocks are used to extract features for PET/CT and PET images in UNet_B network. Thirdly, a hybrid attention mechanism is added to the encoding paths of the UNet_A and UNet_B. Finally, a multiscale feature aggregation block is used for extracting feature maps of different scales of decoding path. On the lung tumor (18)FDGPET/CT multimodal medical images dataset, experiments' results show that the DSC, Recall, VOE, and RVD coefficients of APU-Net are 96.86%, 97.53%, 3.18%, and 3.29%, respectively. APU-Net can improve the segmentation accuracy of the adhesion between the lesion of complex shape and the normal tissue. This has positive significance for computer-aided diagnosis.
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spelling pubmed-91101972022-05-17 APU-Net: An Attention Mechanism Parallel U-Net for Lung Tumor Segmentation Zhou, Tao Dong, YaLi Lu, HuiLing Zheng, XiaoMin Qiu, Shi Hou, SenBao Biomed Res Int Research Article Lung cancer is one of the malignant tumors with high morbidity and mortality, and lung nodules are the early stages of lung cancer. The symptoms of pulmonary nodules are not obvious in the clinic, and the optimal treatment time is missed due to the missed diagnosis in the clinic. A parallel U-Net network called APU-Net is proposed. Firstly, two parallel U-Net networks are used to extract the features of different modalities. Among them, the subnetwork UNet_B extracts the CT image features, and the subnetwork UNet_A consists of two encoders to extract the PET/CT and PET image features. Secondly, multimodal feature extraction blocks are used to extract features for PET/CT and PET images in UNet_B network. Thirdly, a hybrid attention mechanism is added to the encoding paths of the UNet_A and UNet_B. Finally, a multiscale feature aggregation block is used for extracting feature maps of different scales of decoding path. On the lung tumor (18)FDGPET/CT multimodal medical images dataset, experiments' results show that the DSC, Recall, VOE, and RVD coefficients of APU-Net are 96.86%, 97.53%, 3.18%, and 3.29%, respectively. APU-Net can improve the segmentation accuracy of the adhesion between the lesion of complex shape and the normal tissue. This has positive significance for computer-aided diagnosis. Hindawi 2022-05-09 /pmc/articles/PMC9110197/ /pubmed/35586818 http://dx.doi.org/10.1155/2022/5303651 Text en Copyright © 2022 Tao Zhou et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Zhou, Tao
Dong, YaLi
Lu, HuiLing
Zheng, XiaoMin
Qiu, Shi
Hou, SenBao
APU-Net: An Attention Mechanism Parallel U-Net for Lung Tumor Segmentation
title APU-Net: An Attention Mechanism Parallel U-Net for Lung Tumor Segmentation
title_full APU-Net: An Attention Mechanism Parallel U-Net for Lung Tumor Segmentation
title_fullStr APU-Net: An Attention Mechanism Parallel U-Net for Lung Tumor Segmentation
title_full_unstemmed APU-Net: An Attention Mechanism Parallel U-Net for Lung Tumor Segmentation
title_short APU-Net: An Attention Mechanism Parallel U-Net for Lung Tumor Segmentation
title_sort apu-net: an attention mechanism parallel u-net for lung tumor segmentation
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9110197/
https://www.ncbi.nlm.nih.gov/pubmed/35586818
http://dx.doi.org/10.1155/2022/5303651
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