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Orcinol Glucoside Improves Senile Osteoporosis through Attenuating Oxidative Stress and Autophagy of Osteoclast via Activating Nrf2/Keap1 and mTOR Signaling Pathway
Oxidative stress and autophagy play essential roles in the development of senile osteoporosis which is characterized by disrupted osteoclastic bone resorption and osteoblastic bone formation. Orcinol glucoside (OG), a phenolic glycoside isolated from Curculigo orchioides Gaertn, possesses antiosteop...
Autores principales: | Gong, Wan, Liu, Mengqin, Zhang, Qi, Zhang, Quanlong, Wang, Yang, Zhao, Qiming, Xiang, Lu, Zheng, Chengjian, Zhang, Qiaoyan, Qin, Luping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9110208/ https://www.ncbi.nlm.nih.gov/pubmed/35585885 http://dx.doi.org/10.1155/2022/5410377 |
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