Cargando…

Metabolism-Related Bioinformatics Analysis Reveals That HPRT1 Facilitates the Progression of Oral Squamous Cell Carcinoma In Vitro

OBJECTIVES: Many studies have shown that dysregulation of metabolism contributes to oncogenesis. However, the exact roles of metabolism-related genes (MRGs) in oral squamous cell carcinoma (OSCC) remain unclear. Thus, we aimed to identify a prognostic signature related to MRGs in OSCC. METHODS: The...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ye, Hengyu, Zheng, Zenan, Song, Yuxing, Huang, Guangzhao, Wu, Qingqing, Ai, Yilong, Lv, Xiaozhi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9110220/ https://www.ncbi.nlm.nih.gov/pubmed/35586208 http://dx.doi.org/10.1155/2022/7453185

Ejemplares similares

FDCSP Is an Immune-Associated Prognostic Biomarker in HPV-Positive Head and Neck Squamous Carcinoma
por: Wu, Qingqing, et al.
Publicado: (2022)

The Potential Mechanism of Curcumin in Treating Oral Squamous Cell Carcinoma Based on Integrated Bioinformatic Analysis
por: Siyuan, Wu, et al.
Publicado: (2023)

In vitro analysis reveals necroptotic signaling does not provoke DNA damage or HPRT mutations
por: Miles, Mark A., et al.
Publicado: (2020)

Overexpression of HPRT1 is associated with poor prognosis in head and neck squamous cell carcinoma
por: Ahmadi, Mohsen, et al.
Publicado: (2021)

Circular GOLPH3 RNA exerts oncogenic effects in vitro by regulating the miRNA-1299/LIF axis in oral squamous cell carcinoma
por: Zou, Chen, et al.
Publicado: (2022)

METTL3 Intensifies the Progress of Oral Squamous Cell Carcinoma via Modulating the m6A Amount of PRMT5 and PD-L1
por: Ai, Yilong, et al.
Publicado: (2021)

Quantification and molecular characterization of hprt mutants of human T-lymphocytes.
por: Moore, M M, et al.
Publicado: (1993)

The renal phenotype of allopurinol-treated HPRT-deficient mouse
por: Zennaro, Cristina, et al.
Publicado: (2017)

The Study on the Clinical Phenotype and Function of HPRT1 Gene
por: Guo, Miao, et al.
Publicado: (2022)

HPRT1 Promotes Chemoresistance in Oral Squamous Cell Carcinoma via Activating MMP1/PI3K/Akt Signaling Pathway
por: Wu, Tong, et al.
Publicado: (2022)

Hprt mutants in a transplantable murine tumour arise more frequently in vivo than in vitro.
por: Wilkinson, D., et al.
Publicado: (1995)

LINC01355 Contributes to Malignant Phenotype of Oral Squamous Cell Carcinoma and Cytotoxic T Cell Infiltration via Activating Notch Signaling Pathway
por: Zou, Chen, et al.
Publicado: (2021)

Hypoxanthine-guanine phosophoribosyltransferase (HPRT) deficiency: Lesch-Nyhan syndrome
por: Torres, Rosa J, et al.
Publicado: (2007)

PRTFDC1 Is a Genetic Modifier of HPRT-Deficiency in the Mouse
por: Keebaugh, Alaine C., et al.
Publicado: (2011)

HPRT1 activity loss is associated with resistance to thiopurine in ALL
por: Yang, Fan, et al.
Publicado: (2017)

Long non-coding RNA LINC00472 inhibits oral squamous cell carcinoma via miR-4311/GNG7 axis
por: Zou, Chen, et al.
Publicado: (2022)

The HPRT short-term assay in monitoring individuals exposed to genotoxic agents.
por: Montero, R, et al.
Publicado: (1993)

Knockdown of HPRT for Selection of Genetically Modified Human Hematopoietic Progenitor Cells
por: Choudhary, Rashmi, et al.
Publicado: (2013)

Generation of Hprt-disrupted rat through mouse←rat ES chimeras
por: Isotani, Ayako, et al.
Publicado: (2016)

HPRT1 Deficiency Induces Alteration of Mitochondrial Energy Metabolism in the Brain
por: Vinokurov, Andrey Y., et al.
Publicado: (2023)

Circular RNA mitochondrial translation optimization 1 homologue (CircMTO1) induced by zinc finger protein 460 (ZNF460) promotes oral squamous cell carcinoma progression through the microRNA miR-320a / alpha thalassemia/mental retardation, X-linked (ATRX) axis
por: Zou, Chen, et al.
Publicado: (2021)

HPRT Mutations in Lymphocytes from 1,3-Butadiene-Exposed Workers in China
por: Liu, Shengxue, et al.
Publicado: (2008)

Enriching CRISPR-Cas9 targeted cells by co-targeting the HPRT gene
por: Liao, Shuren, et al.
Publicado: (2015)

hprt mutant lymphocyte frequencies in workers at a 1,3-butadiene production plant.
por: Ward, J B, et al.
Publicado: (1994)

Use of the HPRT gene to study nuclease-induced DNA double-strand break repair
por: Gravells, Polly, et al.
Publicado: (2015)

A Trivalent Enzymatic System for Uricolytic Therapy of HPRT Deficiency and Lesch-Nyhan Disease
por: Ronda, Luca, et al.
Publicado: (2017)

Evolution of (p)ppGpp-HPRT regulation through diversification of an allosteric oligomeric interaction
por: Anderson, Brent W, et al.
Publicado: (2019)

Effects of Titanium Dioxide Nanoparticles on the Hprt Gene Mutations in V79 Hamster Cells
por: Kazimirova, Alena, et al.
Publicado: (2020)

IMPDH2 and HPRT expression and a prognostic significance in preoperative and postoperative patients with osteosarcoma
por: Chaiyawat, Parunya, et al.
Publicado: (2021)

LINC00941 promotes oral squamous cell carcinoma progression via activating CAPRIN2 and canonical WNT/β‐catenin signaling pathway
por: Ai, Yilong, et al.
Publicado: (2020)

Small Duplication of HPRT 1 Gene May Be Causative For Lesh-Nyhan Disease in Iranian Patients
por: BOROUJERDI, Razieh, et al.
Publicado: (2015)

Impact of nanosilver on various DNA lesions and HPRT gene mutations – effects of charge and surface coating
por: Huk, Anna, et al.
Publicado: (2015)

Expression variation of OGG1 and HPRT gene and DNA damage in arsenic exposed industrial workers
por: Akram, Zertashia, et al.
Publicado: (2022)

M6A-related bioinformatics analysis reveals that HNRNPC facilitates progression of OSCC via EMT
por: Huang, Guang-Zhao, et al.
Publicado: (2020)

Bioinformatic Analysis of Plus Gene Expression Related to Progression from Leukoplakia to Oral Squamous Cell Carcinoma
por: de Avila, Jaime Guzman, et al.
Publicado: (2022)

Molecular analysis of hypoxanthine guanine phosphoribosyltransferase (HPRT) gene in five Korean families with Lesch-Nyhan syndrome.
por: Kim, K. J., et al.
Publicado: (1997)

lncRNA DCST1-AS1 Facilitates Oral Squamous Cell Carcinoma by Promoting M2 Macrophage Polarization through Activating NF-κB Signaling
por: Ai, Yilong, et al.
Publicado: (2021)

Bioinformatics Analyses Indicate That Cathepsin G (CTSG) is a Potential Immune-Related Biomarker in Oral Squamous Cell Carcinoma (OSCC)
por: Huang, Guang-zhao, et al.
Publicado: (2021)

Qualitatively and quantitatively similar effects of active and passive maternal tobacco smoke exposure on in utero mutagenesis at the HPRT locus
por: Grant, Stephen G
Publicado: (2005)

Assessment of 1,3-butadiene exposure in polymer production workers using HPRT mutations in lymphocytes as a biomarker.
por: Ammenheuser, M M, et al.
Publicado: (2001)

Cannot write session to /tmp/vufind_sessions/sess_5mlchmiq4hasaf3f66oc6k1e8m