Long-Term Follow-Up of Refractory Large Macular Hole with Autologous Neurosensory Retinal Free Flap Transplantation

PURPOSE: To evaluate the long-term anatomic and functional outcomes of autologous neurosensory retinal free flap transplantation (ART) for patients with refractory large macular hole (MH). DESIGN: Retrospective interventional case series. METHODS: We reviewed 9 patients who underwent ART for their r...

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Detalles Bibliográficos
Autores principales: Lee, Po-Yen, Chang, Yo-Chen, Liu, Pei-Kang, Kao, Tzu-En, Wu, Horng-Jiun, Chen, Kuo-Jen, Wu, Kwou-Yeung, Cheng, Kai-Chun, Wu, Wen-Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9110223/
https://www.ncbi.nlm.nih.gov/pubmed/35586596
http://dx.doi.org/10.1155/2022/1717366
Descripción
Sumario:PURPOSE: To evaluate the long-term anatomic and functional outcomes of autologous neurosensory retinal free flap transplantation (ART) for patients with refractory large macular hole (MH). DESIGN: Retrospective interventional case series. METHODS: We reviewed 9 patients who underwent ART for their refractory large MH. In this extended follow-up study, postoperative assessment including spectral-domain optical coherence tomography and best-corrected visual acuity (BCVA) were recorded at 12, 15, 18, 21, and 24 months after surgery. RESULTS: The macular hole of all patients appeared successfully closed during the whole follow-up period. The mean logMAR BCVA improved from 1.61 ± 0.44 (preoperative) to 0.72 ± 0.30 (12 months after surgery) (p < 0.001). Thereafter, the mean BCVA remained stable at each follow-up. At the mean 16.0 ± 0.8 months postoperatively, inner retinal cystic changes were observed in 4 eyes (44.4%), but these did not significantly affect vision. CONCLUSION: ART is a good alternative technique for closing large refractory macular holes. Although inner retinal cystic changes were observed in 4 eyes (44.4%), this phenomenon did not significantly affect visual acuity. It provides long-term good anatomical and functional results, especially in cases where insufficient ILM or lens capsule are left.