Can SpRY recognize any PAM in human cells?

The application of clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated proteins (Cas) can be limited due to a lack of compatible protospacer adjacent motif (PAM) sequences in the DNA regions of interest. Recently, SpRY, a variant of Streptococcus pyogenes Cas9 (S...

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Detalles Bibliográficos
Autores principales: YE, Jinbin, XI, Haitao, CHEN, Yilu, CHEN, Qishu, LU, Xiaosheng, LV, Jineng, CHEN, Yamin, GU, Feng, ZHAO, Junzhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Zhejiang University Press 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9110322/
https://www.ncbi.nlm.nih.gov/pubmed/35557039
http://dx.doi.org/10.1631/jzus.B2100710

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9110322/
https://www.ncbi.nlm.nih.gov/pubmed/35557039
http://dx.doi.org/10.1631/jzus.B2100710

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