Multifunctional metal-organic framework-based nanoreactor for starvation/oxidation improved indoleamine 2,3-dioxygenase-blockade tumor immunotherapy

Inhibited immune response and low levels of delivery restrict starvation cancer therapy efficacy. Here, we report on the co-delivery of glucose oxidase (GOx) and indoleamine 2,3-dioxygenase (IDO) inhibitor 1-methyltryptophan using a metal-organic framework (MOF)-based nanoreactor, showing an amplifi...

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Detalles Bibliográficos
Autores principales: Dai, Liangliang, Yao, Mengjiao, Fu, Zhenxiang, Li, Xiang, Zheng, Xinmin, Meng, Siyu, Yuan, Zhang, Cai, Kaiyong, Yang, Hui, Zhao, Yanli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9110376/
https://www.ncbi.nlm.nih.gov/pubmed/35577812
http://dx.doi.org/10.1038/s41467-022-30436-y

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