Purine nucleotide depletion prompts cell migration by stimulating the serine synthesis pathway

Purine nucleotides are necessary for various biological processes related to cell proliferation. Despite their importance in DNA and RNA synthesis, cellular signaling, and energy-dependent reactions, the impact of changes in cellular purine levels on cell physiology remains poorly understood. Here,...

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Detalles Bibliográficos
Autores principales: Soflaee, Mona Hoseini, Kesavan, Rushendhiran, Sahu, Umakant, Tasdogan, Alpaslan, Villa, Elodie, Djabari, Zied, Cai, Feng, Tran, Diem H., Vu, Hieu S., Ali, Eunus S., Rion, Halie, O’Hara, Brendan P., Kelekar, Sherwin, Hallett, James Hughes, Martin, Misty, Mathews, Thomas P., Gao, Peng, Asara, John M., Manning, Brendan D., Ben-Sahra, Issam, Hoxhaj, Gerta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9110385/
https://www.ncbi.nlm.nih.gov/pubmed/35577785
http://dx.doi.org/10.1038/s41467-022-30362-z

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