Inducing respiratory complex I impairment elicits an increase in PGC1α in ovarian cancer

Anticancer strategies aimed at inhibiting Complex I of the mitochondrial respiratory chain are increasingly being attempted in solid tumors, as functional oxidative phosphorylation is vital for cancer cells. Using ovarian cancer as a model, we show that a compensatory response to an energy crisis in...

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Detalles Bibliográficos
Autores principales: De Luise, Monica, Sollazzo, Manuela, Lama, Eleonora, Coadă, Camelia Alexandra, Bressi, Licia, Iorio, Maria, Cavina, Beatrice, D’Angelo, Luigi, Milioni, Sara, Marchio, Lorena, Miglietta, Stefano, Coluccelli, Sara, Tedesco, Greta, Ghelli, Anna, Lemma, Silvia, Perrone, Anna Myriam, Kurelac, Ivana, Iommarini, Luisa, Porcelli, Anna Maria, Gasparre, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9110394/
https://www.ncbi.nlm.nih.gov/pubmed/35577908
http://dx.doi.org/10.1038/s41598-022-11620-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9110394/
https://www.ncbi.nlm.nih.gov/pubmed/35577908
http://dx.doi.org/10.1038/s41598-022-11620-y

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