Ca(2+)-mediated higher-order assembly of heterodimers in amino acid transport system b(0,+) biogenesis and cystinuria

Cystinuria is a genetic disorder characterized by overexcretion of dibasic amino acids and cystine, causing recurrent kidney stones and kidney failure. Mutations of the regulatory glycoprotein rBAT and the amino acid transporter b(0,+)AT, which constitute system b(0,+), are linked to type I and non-...

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Detalles Bibliográficos
Autores principales: Lee, Yongchan, Wiriyasermkul, Pattama, Kongpracha, Pornparn, Moriyama, Satomi, Mills, Deryck J., Kühlbrandt, Werner, Nagamori, Shushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9110406/
https://www.ncbi.nlm.nih.gov/pubmed/35577790
http://dx.doi.org/10.1038/s41467-022-30293-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9110406/
https://www.ncbi.nlm.nih.gov/pubmed/35577790
http://dx.doi.org/10.1038/s41467-022-30293-9

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