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Ca(2+)-mediated higher-order assembly of heterodimers in amino acid transport system b(0,+) biogenesis and cystinuria
Cystinuria is a genetic disorder characterized by overexcretion of dibasic amino acids and cystine, causing recurrent kidney stones and kidney failure. Mutations of the regulatory glycoprotein rBAT and the amino acid transporter b(0,+)AT, which constitute system b(0,+), are linked to type I and non-...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9110406/ https://www.ncbi.nlm.nih.gov/pubmed/35577790 http://dx.doi.org/10.1038/s41467-022-30293-9 |