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A high resolution scanning electron microscopy analysis of intracranial thrombi embedded along the stent retrievers

Endovascular treatment with stent retriever thrombectomy is a major advancement in the standard of care in acute ischemic stroke (AIS). The modalities through which thrombi embed along stent retriever following mechanical thrombectomy (MTB) have not yet been elucidated. Using scanning electron micro...

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Detalles Bibliográficos
Autores principales: Dumitriu LaGrange, Daniela, Bernava, Gianmarco, Reymond, Philippe, Wanke, Isabel, Vargas, Maria Isabel, Machi, Paolo, Lövblad, Karl-Olof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9110407/
https://www.ncbi.nlm.nih.gov/pubmed/35577906
http://dx.doi.org/10.1038/s41598-022-11830-4
Descripción
Sumario:Endovascular treatment with stent retriever thrombectomy is a major advancement in the standard of care in acute ischemic stroke (AIS). The modalities through which thrombi embed along stent retriever following mechanical thrombectomy (MTB) have not yet been elucidated. Using scanning electron microscopy (SEM), we analyzed the appearance of thrombi retrieved by MTB from AIS patients, when embedded into the stent retriever. We observed that the organization and structural compactness vary for compositionally different thrombi. The modalities of attachment onto the stent vary according to thrombus composition and organization.