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A high resolution scanning electron microscopy analysis of intracranial thrombi embedded along the stent retrievers

Endovascular treatment with stent retriever thrombectomy is a major advancement in the standard of care in acute ischemic stroke (AIS). The modalities through which thrombi embed along stent retriever following mechanical thrombectomy (MTB) have not yet been elucidated. Using scanning electron micro...

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Autores principales: Dumitriu LaGrange, Daniela, Bernava, Gianmarco, Reymond, Philippe, Wanke, Isabel, Vargas, Maria Isabel, Machi, Paolo, Lövblad, Karl-Olof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9110407/
https://www.ncbi.nlm.nih.gov/pubmed/35577906
http://dx.doi.org/10.1038/s41598-022-11830-4
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author Dumitriu LaGrange, Daniela
Bernava, Gianmarco
Reymond, Philippe
Wanke, Isabel
Vargas, Maria Isabel
Machi, Paolo
Lövblad, Karl-Olof
author_facet Dumitriu LaGrange, Daniela
Bernava, Gianmarco
Reymond, Philippe
Wanke, Isabel
Vargas, Maria Isabel
Machi, Paolo
Lövblad, Karl-Olof
author_sort Dumitriu LaGrange, Daniela
collection PubMed
description Endovascular treatment with stent retriever thrombectomy is a major advancement in the standard of care in acute ischemic stroke (AIS). The modalities through which thrombi embed along stent retriever following mechanical thrombectomy (MTB) have not yet been elucidated. Using scanning electron microscopy (SEM), we analyzed the appearance of thrombi retrieved by MTB from AIS patients, when embedded into the stent retriever. We observed that the organization and structural compactness vary for compositionally different thrombi. The modalities of attachment onto the stent vary according to thrombus composition and organization.
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spelling pubmed-91104072022-05-18 A high resolution scanning electron microscopy analysis of intracranial thrombi embedded along the stent retrievers Dumitriu LaGrange, Daniela Bernava, Gianmarco Reymond, Philippe Wanke, Isabel Vargas, Maria Isabel Machi, Paolo Lövblad, Karl-Olof Sci Rep Article Endovascular treatment with stent retriever thrombectomy is a major advancement in the standard of care in acute ischemic stroke (AIS). The modalities through which thrombi embed along stent retriever following mechanical thrombectomy (MTB) have not yet been elucidated. Using scanning electron microscopy (SEM), we analyzed the appearance of thrombi retrieved by MTB from AIS patients, when embedded into the stent retriever. We observed that the organization and structural compactness vary for compositionally different thrombi. The modalities of attachment onto the stent vary according to thrombus composition and organization. Nature Publishing Group UK 2022-05-16 /pmc/articles/PMC9110407/ /pubmed/35577906 http://dx.doi.org/10.1038/s41598-022-11830-4 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Dumitriu LaGrange, Daniela
Bernava, Gianmarco
Reymond, Philippe
Wanke, Isabel
Vargas, Maria Isabel
Machi, Paolo
Lövblad, Karl-Olof
A high resolution scanning electron microscopy analysis of intracranial thrombi embedded along the stent retrievers
title A high resolution scanning electron microscopy analysis of intracranial thrombi embedded along the stent retrievers
title_full A high resolution scanning electron microscopy analysis of intracranial thrombi embedded along the stent retrievers
title_fullStr A high resolution scanning electron microscopy analysis of intracranial thrombi embedded along the stent retrievers
title_full_unstemmed A high resolution scanning electron microscopy analysis of intracranial thrombi embedded along the stent retrievers
title_short A high resolution scanning electron microscopy analysis of intracranial thrombi embedded along the stent retrievers
title_sort high resolution scanning electron microscopy analysis of intracranial thrombi embedded along the stent retrievers
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9110407/
https://www.ncbi.nlm.nih.gov/pubmed/35577906
http://dx.doi.org/10.1038/s41598-022-11830-4
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