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Cannabidiol but not cannabidiolic acid reduces behavioural sensitisation to methamphetamine in rats, at pharmacologically effective doses

RATIONALE: Cannabidiol (CBD) and cannabidiolic acid (CBDA) are non-psychoactive components of the cannabis plant. CBD has been well characterised to have anxiolytic and anticonvulsant activity, whereas the behavioural effects of CBDA are less clear. Preclinical and clinical data suggests that CBD ha...

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Detalles Bibliográficos
Autores principales: Umpierrez, Laísa S., Costa, Priscila A., Michelutti, Eden A., Baracz, Sarah J., Sauer, Melanie, Turner, Anita J., Everett, Nicholas A., Arnold, Jonathon C., McGregor, Iain S., Cornish, Jennifer L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9110442/
https://www.ncbi.nlm.nih.gov/pubmed/35435462
http://dx.doi.org/10.1007/s00213-022-06119-3