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Cannabidiol but not cannabidiolic acid reduces behavioural sensitisation to methamphetamine in rats, at pharmacologically effective doses
RATIONALE: Cannabidiol (CBD) and cannabidiolic acid (CBDA) are non-psychoactive components of the cannabis plant. CBD has been well characterised to have anxiolytic and anticonvulsant activity, whereas the behavioural effects of CBDA are less clear. Preclinical and clinical data suggests that CBD ha...
Autores principales: | Umpierrez, Laísa S., Costa, Priscila A., Michelutti, Eden A., Baracz, Sarah J., Sauer, Melanie, Turner, Anita J., Everett, Nicholas A., Arnold, Jonathon C., McGregor, Iain S., Cornish, Jennifer L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9110442/ https://www.ncbi.nlm.nih.gov/pubmed/35435462 http://dx.doi.org/10.1007/s00213-022-06119-3 |
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