The role of the individual TOM subunits in the association of PINK1 with depolarized mitochondria

ABSTRACT: Mitochondria dysfunction is involved in the pathomechanism of many illnesses including Parkinson’s disease. PINK1, which is mutated in some cases of familial Parkinsonism, is a key component in the degradation of damaged mitochondria by mitophagy. The accumulation of PINK1 on the mitochond...

Descripción completa

Detalles Bibliográficos
Autores principales: Maruszczak, Klaudia K., Jung, Martin, Rasool, Shafqat, Trempe, Jean-François, Rapaport, Doron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9110474/
https://www.ncbi.nlm.nih.gov/pubmed/35391620
http://dx.doi.org/10.1007/s00109-022-02191-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9110474/
https://www.ncbi.nlm.nih.gov/pubmed/35391620
http://dx.doi.org/10.1007/s00109-022-02191-6

Ejemplares similares