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The role of the individual TOM subunits in the association of PINK1 with depolarized mitochondria
ABSTRACT: Mitochondria dysfunction is involved in the pathomechanism of many illnesses including Parkinson’s disease. PINK1, which is mutated in some cases of familial Parkinsonism, is a key component in the degradation of damaged mitochondria by mitophagy. The accumulation of PINK1 on the mitochond...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9110474/ https://www.ncbi.nlm.nih.gov/pubmed/35391620 http://dx.doi.org/10.1007/s00109-022-02191-6 |