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ASK1 is a novel molecular target for preventing aminoglycoside-induced hair cell death

ABSTRACT: Aminoglycoside antibiotics are lifesaving medicines, crucial for the treatment of chronic or drug resistant infections. However, aminoglycosides are toxic to the sensory hair cells in the inner ear. As a result, aminoglycoside-treated individuals can develop permanent hearing loss and vest...

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Detalles Bibliográficos
Autores principales: Ogier, Jacqueline M., Gao, Yujing, Dunne, Eileen M., Wilson, Michael A., Ranganathan, Sarath C., Tesch, Gregory H., Nikolic Paterson, David J., Dabdoub, Alain, Burt, Rachel A., Nayagam, Bryony A., Lockhart, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9110505/
https://www.ncbi.nlm.nih.gov/pubmed/35471608
http://dx.doi.org/10.1007/s00109-022-02188-1

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