Inhibition of p38 MAPK decreases hyperglycemia-induced nephrin endocytosis and attenuates albuminuria

ABSTRACT: Chronic hyperglycemia, as in diabetes mellitus, may cause glomerular damage with microalbuminuria as an early sign. Noteworthy, even acute hyperglycemia can increase glomerular permeability before structural damage of the glomerular filter can be detected. Despite intensive research, speci...

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Detalles Bibliográficos
Autores principales: Woznowski, Magdalena Patrycja, Potthoff, Sebastian Alexander, Königshausen, Eva, Haase, Raphael, Hoch, Henning, Meyer-Schwesinger, Catherine, Wiech, Thorsten, Stegbauer, Johannes, Rump, Lars Christian, Sellin, Lorenz, Quack, Ivo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9110524/
https://www.ncbi.nlm.nih.gov/pubmed/35451598
http://dx.doi.org/10.1007/s00109-022-02184-5

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