The angiopoietin-Tie2 pathway regulates Purkinje cell dendritic morphogenesis in a cell-autonomous manner

Neuro-vascular communication is essential to synchronize central nervous system development. Here, we identify angiopoietin/Tie2 as a neuro-vascular signaling axis involved in regulating dendritic morphogenesis of Purkinje cells (PCs). We show that in the developing cerebellum Tie2 expression is not...

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Detalles Bibliográficos
Autores principales: Luck, Robert, Karakatsani, Andromachi, Shah, Bhavin, Schermann, Geza, Adler, Heike, Kupke, Janina, Tisch, Nathalie, Jeong, Hyun-Woo, Kerstin Back, Michaela, Hetsch, Florian, D’Errico, Anna, Palma, Michele De, Wiedtke, Ellen, Grimm, Dirk, Acker-Palmer, Amparo, von Engelhardt, Jakob, Adams, Ralf H., Augustin, Hellmut G., de Almodóvar, Carmen Ruiz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9110807/
https://www.ncbi.nlm.nih.gov/pubmed/34407407
http://dx.doi.org/10.1016/j.celrep.2021.109522

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