Cargando…

Intranasal Delivery of Thermostable Subunit Vaccine for Cross-Reactive Mucosal and Systemic Antibody Responses Against SARS-CoV-2

Despite the remarkable efficacy of currently approved COVID-19 vaccines, there are several opportunities for continued vaccine development against SARS-CoV-2 and future lethal respiratory viruses. In particular, restricted vaccine access and hesitancy have limited immunization rates. In addition, cu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nguyen, Khue G., Mantooth, Siena M., Vrabel, Maura R., Zaharoff, David A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9110812/ https://www.ncbi.nlm.nih.gov/pubmed/35592324 http://dx.doi.org/10.3389/fimmu.2022.858904

Ejemplares similares

Localized Interleukin-12 for Cancer Immunotherapy
por: Nguyen, Khue G., et al.
Publicado: (2020)

Focal Cryo-Immunotherapy with Intratumoral IL-12 Prevents Recurrence of Large Murine Tumors
por: Vrabel, Maura R., et al.
Publicado: (2023)

A Thermostable Oral SARS-CoV-2 Vaccine Induces Mucosal and Protective Immunity
por: Bellier, Bertrand, et al.
Publicado: (2022)

Intranasal Lentiviral Vector-Mediated Antibody Delivery Confers Reduction of SARS-CoV-2 Infection in Elderly and Immunocompromised Mice
por: Du, Yue, et al.
Publicado: (2022)

Mucosal Immunity and Protective Efficacy of Intranasal Inactivated Influenza Vaccine Is Improved by Chitosan Nanoparticle Delivery in Pigs
por: Dhakal, Santosh, et al.
Publicado: (2018)

Potentiating Lung Mucosal Immunity Through Intranasal Vaccination
por: Nelson, Sean A., et al.
Publicado: (2021)

An Intranasal OMV-Based Vaccine Induces High Mucosal and Systemic Protecting Immunity Against a SARS-CoV-2 Infection
por: van der Ley, Peter A., et al.
Publicado: (2021)

Intranasal Single-Replication Influenza Vector Induces Cross-Reactive Serum and Mucosal Antibodies against SARS-CoV-2 Variants
por: Moser, Michael J., et al.
Publicado: (2023)

Intranasal Delivery of MVA Vector Vaccine Induces Effective Pulmonary Immunity Against SARS-CoV-2 in Rodents
por: Bošnjak, Berislav, et al.
Publicado: (2021)

Intranasal Delivery of RIG-I Agonist Drives Pulmonary Myeloid Cell Activation in Mice
por: Nair, Sajith, et al.
Publicado: (2022)

Protection from COVID-19 disease in hamsters vaccinated with subunit SARS-CoV-2 S1 mucosal vaccines adjuvanted with different adjuvants
por: Sui, Yongjun, et al.
Publicado: (2023)

Characterization of Systemic and Mucosal Humoral Immune Responses to an Adjuvanted Intranasal SARS-CoV-2 Protein Subunit Vaccine Candidate in Mice
por: Maltseva, Mariam, et al.
Publicado: (2022)

SARS-CoV-2 mRNA vaccination induces an intranasal mucosal response characterized by neutralizing antibodies
por: Cao, Kevin T., et al.
Publicado: (2023)

Differences in systemic and mucosal SARS-CoV-2 antibody prevalence in a prospective cohort of Dutch children
por: Keuning, Maya W., et al.
Publicado: (2022)

Nasal delivery of thermostable and broadly neutralizing antibodies protects mice against SARS-CoV-2 infection
por: Fan, Wenhui, et al.
Publicado: (2022)

Intranasal Delivery of Influenza Subunit Vaccine Formulated with GEM Particles as an Adjuvant
por: Saluja, Vinay, et al.
Publicado: (2010)

Combined Subcutaneous-Intranasal Immunization With Epitope-Based Antigens Elicits Binding and Neutralizing Antibody Responses in Serum and Mucosae Against PRRSV-2 and SARS-CoV-2
por: Fragoso-Saavedra, Mario, et al.
Publicado: (2022)

Sublingual Priming with a HIV gp41-Based Subunit Vaccine Elicits Mucosal Antibodies and Persistent B Memory Responses in Non-Human Primates
por: Bekri, Selma, et al.
Publicado: (2017)

Interferon-λ Improves the Efficacy of Intranasally or Rectally Administered Influenza Subunit Vaccines by a Thymic Stromal Lymphopoietin-Dependent Mechanism
por: Ye, Liang, et al.
Publicado: (2021)

Reactive T Cells in Convalescent COVID-19 Patients With Negative SARS-CoV-2 Antibody Serology
por: Steiner, Sophie, et al.
Publicado: (2021)

Evaluating SARS-CoV-2 antibody reactivity to natural exposure and inactivated vaccination with peptide microarrays
por: Zheng, Peiyan, et al.
Publicado: (2023)

mRNA vaccination drives differential mucosal neutralizing antibody profiles in naïve and SARS-CoV-2 previously-infected individuals
por: Longet, Stephanie, et al.
Publicado: (2022)

Cross-reactive antibodies after SARS-CoV-2 infection and vaccination
por: Grobben, Marloes, et al.
Publicado: (2021)

Heterologous Systemic Prime–Intranasal Boosting Using a Spore SARS-CoV-2 Vaccine Confers Mucosal Immunity and Cross-Reactive Antibodies in Mice as well as Protection in Hamsters
por: Katsande, Paidamoyo M., et al.
Publicado: (2022)

Cross-Reactive SARS-CoV-2 Neutralizing Antibodies From Deep Mining of Early Patient Responses
por: Bullen, Georgia, et al.
Publicado: (2021)

Intranasally inoculated bacterium-like particles displaying porcine epidemic diarrhea virus S1 protein induced intestinal mucosal immune response in mice
por: Su, Kai, et al.
Publicado: (2023)

Editorial: Mucosal immunity to HIV and SARS-CoV-2 infection and vaccination
por: Bomsel, Morgane, et al.
Publicado: (2023)

An intranasal vaccine targeting the receptor binding domain of SARS-CoV-2 elicits a protective immune response
por: Chen, Li, et al.
Publicado: (2022)

Systemic and Mucosal Antibody Responses to Soluble and Nanoparticle-Conjugated Antigens Administered Intranasally
por: Howe, Savannah E., et al.
Publicado: (2016)

Antibodies and Their Receptors: Different Potential Roles in Mucosal Defense
por: Horton, Rachel E., et al.
Publicado: (2013)

Gut Mucosal Antibody Responses and Implications for Food Allergy
por: Hoh, Ramona A., et al.
Publicado: (2018)

Bacterium-Like Particles for Efficient Immune Stimulation of Existing Vaccines and New Subunit Vaccines in Mucosal Applications
por: Van Braeckel-Budimir, Natalija, et al.
Publicado: (2013)

Differential Biodistribution of Adenoviral-Vectored Vaccine Following Intranasal and Endotracheal Deliveries Leads to Different Immune Outcomes
por: Jeyanathan, Vidthiya, et al.
Publicado: (2022)

Repurposing mucosal delivery devices for live attenuated tuberculosis vaccines
por: Puri, Munish, et al.
Publicado: (2023)

Colony stimulating factors secreted by irradiated autologous tumor cell vaccines inhibit immunity
por: Ravindranathan, Sruthi, et al.
Publicado: (2015)

The Mucosal and Serological Immune Responses to the Novel Coronavirus (SARS-CoV-2) Vaccines
por: Chan, Renee W. Y., et al.
Publicado: (2021)

Mucosal immunity: The missing link in comprehending SARS-CoV-2 infection and transmission
por: Russell, Michael W., et al.
Publicado: (2022)

Corrigendum: Differential biodistribution of adenoviral-vectored vaccine following intranasal and endotracheal deliveries leads to different immune outcomes
por: Jeyanathan, Vidthiya, et al.
Publicado: (2023)

Functional Analysis of Human and Feline Coronavirus Cross-Reactive Antibodies Directed Against the SARS-CoV-2 Fusion Peptide
por: Vanderheijden, Nathalie, et al.
Publicado: (2022)

Mucosal and Systemic Immune Responses to Influenza H7N9 Antigen HA1–2 Co-Delivered Intranasally with Flagellin or Polyethyleneimine in Mice and Chickens
por: Song, Li, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_ihn3bfau9arcvhrehlsodn9bop