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Dexamethasone resets stable association of nuclear Snail with LSD1 concomitant with transition from EMT to partial EMT

Cancer cells utilize epithelial to mesenchymal transition (EMT) during invasion and metastasis. This program has intermediate cell states with retained epithelial and gained mesenchymal features together, referred to as partial EMT. Histone demethylase LSD1 forms a complex with the EMT master transc...

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Detalles Bibliográficos
Autores principales: Okuda, Satoshi, Yamakado, Nao, Higashikawa, Koichiro, Uetsuki, Ryo, Ishida, Fumi, Rizqiawan, Andra, Ono, Shigehiro, Mizuta, Kuniko, Kamata, Nobuyuki, Tobiume, Kei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9110894/
https://www.ncbi.nlm.nih.gov/pubmed/35592611
http://dx.doi.org/10.1016/j.bbrep.2022.101277