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Scoparone Improves Nonalcoholic Steatohepatitis Through Alleviating JNK/Sab Signaling Pathway-Mediated Mitochondrial Dysfunction

The activated c-Jun N-terminal kinase (JNK) specifically combined with SH3 domain-binding protein 5 (Sab) may mediate damage to the mitochondrial respiratory chain. Whether mitochondrial dysfunction induced by the JNK/Sab signaling pathway plays a pivotal role in the lipotoxic injury of nonalcoholic...

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Detalles Bibliográficos
Autores principales:	Jiang, Yuwei, Xu, Jiaoya, Huang, Ping, Yang, Lili, Liu, Yang, Li, Yiping, Wang, Jue, Song, Haiyan, Zheng, Peiyong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9110978/ https://www.ncbi.nlm.nih.gov/pubmed/35592421 http://dx.doi.org/10.3389/fphar.2022.863756

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