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Recent Progress on Rapid Lateral Flow Assay-Based Early Diagnosis of COVID-19
The outbreak of the coronavirus disease 2019 (COVID-19) has resulted in enormous losses worldwide. Through effective control measures and vaccination, prevention and curbing have proven significantly effective; however, the disease has still not been eliminated. Therefore, it is necessary to develop...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9111179/ https://www.ncbi.nlm.nih.gov/pubmed/35592553 http://dx.doi.org/10.3389/fbioe.2022.866368 |
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author | Zhang, Ying Chai, Yujuan Hu, Zulu Xu, Zhourui Li, Meirong Chen, Xin Yang, Chengbin Liu, Jia |
author_facet | Zhang, Ying Chai, Yujuan Hu, Zulu Xu, Zhourui Li, Meirong Chen, Xin Yang, Chengbin Liu, Jia |
author_sort | Zhang, Ying |
collection | PubMed |
description | The outbreak of the coronavirus disease 2019 (COVID-19) has resulted in enormous losses worldwide. Through effective control measures and vaccination, prevention and curbing have proven significantly effective; however, the disease has still not been eliminated. Therefore, it is necessary to develop a simple, convenient, and rapid detection strategy for controlling disease recurrence and transmission. Taking advantage of their low-cost and simple operation, point-of-care test (POCT) kits for COVID-19 based on the lateral flow assay (LFA) chemistry have become one of the most convenient and widely used screening tools for pathogens in hospitals and at home. In this review, we introduce essential features of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus, compare existing detection methods, and focus on the principles, merits and limitations of the LFAs based on viral nucleic acids, antigens, and corresponding antibodies. A systematic comparison was realized through summarization and analyses, providing a comprehensive demonstration of the LFA technology and insights into preventing and curbing the COVID-19 pandemic. |
format | Online Article Text |
id | pubmed-9111179 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-91111792022-05-18 Recent Progress on Rapid Lateral Flow Assay-Based Early Diagnosis of COVID-19 Zhang, Ying Chai, Yujuan Hu, Zulu Xu, Zhourui Li, Meirong Chen, Xin Yang, Chengbin Liu, Jia Front Bioeng Biotechnol Bioengineering and Biotechnology The outbreak of the coronavirus disease 2019 (COVID-19) has resulted in enormous losses worldwide. Through effective control measures and vaccination, prevention and curbing have proven significantly effective; however, the disease has still not been eliminated. Therefore, it is necessary to develop a simple, convenient, and rapid detection strategy for controlling disease recurrence and transmission. Taking advantage of their low-cost and simple operation, point-of-care test (POCT) kits for COVID-19 based on the lateral flow assay (LFA) chemistry have become one of the most convenient and widely used screening tools for pathogens in hospitals and at home. In this review, we introduce essential features of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus, compare existing detection methods, and focus on the principles, merits and limitations of the LFAs based on viral nucleic acids, antigens, and corresponding antibodies. A systematic comparison was realized through summarization and analyses, providing a comprehensive demonstration of the LFA technology and insights into preventing and curbing the COVID-19 pandemic. Frontiers Media S.A. 2022-05-03 /pmc/articles/PMC9111179/ /pubmed/35592553 http://dx.doi.org/10.3389/fbioe.2022.866368 Text en Copyright © 2022 Zhang, Chai, Hu, Xu, Li, Chen, Yang and Liu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Bioengineering and Biotechnology Zhang, Ying Chai, Yujuan Hu, Zulu Xu, Zhourui Li, Meirong Chen, Xin Yang, Chengbin Liu, Jia Recent Progress on Rapid Lateral Flow Assay-Based Early Diagnosis of COVID-19 |
title | Recent Progress on Rapid Lateral Flow Assay-Based Early Diagnosis of COVID-19 |
title_full | Recent Progress on Rapid Lateral Flow Assay-Based Early Diagnosis of COVID-19 |
title_fullStr | Recent Progress on Rapid Lateral Flow Assay-Based Early Diagnosis of COVID-19 |
title_full_unstemmed | Recent Progress on Rapid Lateral Flow Assay-Based Early Diagnosis of COVID-19 |
title_short | Recent Progress on Rapid Lateral Flow Assay-Based Early Diagnosis of COVID-19 |
title_sort | recent progress on rapid lateral flow assay-based early diagnosis of covid-19 |
topic | Bioengineering and Biotechnology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9111179/ https://www.ncbi.nlm.nih.gov/pubmed/35592553 http://dx.doi.org/10.3389/fbioe.2022.866368 |
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