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Cardiac surgery on patients with COVID‐19: a systematic review and meta‐analysis

INTRODUCTION: The COVID‐19 pandemic has had a significant impact on global surgery. In particular, deleterious effects of SARS‐CoV‐2 infection on the heart and cardiovascular system have been described. To inform surgical patients, we performed a systematic review and meta‐analysis aiming to charact...

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Autores principales: Gupta, Aashray K., Leslie, Alasdair, Hewitt, Joseph N., Kovoor, Joshua G., Ovenden, Christopher D., Edwards, Suzanne, Chan, Justin C. Y., Worthington, Michael G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9111466/
https://www.ncbi.nlm.nih.gov/pubmed/35373439
http://dx.doi.org/10.1111/ans.17667
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author Gupta, Aashray K.
Leslie, Alasdair
Hewitt, Joseph N.
Kovoor, Joshua G.
Ovenden, Christopher D.
Edwards, Suzanne
Chan, Justin C. Y.
Worthington, Michael G.
author_facet Gupta, Aashray K.
Leslie, Alasdair
Hewitt, Joseph N.
Kovoor, Joshua G.
Ovenden, Christopher D.
Edwards, Suzanne
Chan, Justin C. Y.
Worthington, Michael G.
author_sort Gupta, Aashray K.
collection PubMed
description INTRODUCTION: The COVID‐19 pandemic has had a significant impact on global surgery. In particular, deleterious effects of SARS‐CoV‐2 infection on the heart and cardiovascular system have been described. To inform surgical patients, we performed a systematic review and meta‐analysis aiming to characterize outcomes of COVID‐19 positive patients undergoing cardiac surgery. METHODS: The study protocol was registered with PROSPERO (CRD42021228533) and conformed with PRISMA 2020 and MOOSE guidelines. PubMed, Ovid MEDLINE and Web of Science were searched between 1 January 2019 to 24 February 2022 for studies reporting outcomes on COVID‐19 positive patients undergoing cardiac surgery. Study screening, data extraction and risk of bias assessment were conducted in duplicate. Meta‐analysis was conducted using a random‐effects model where at least two studies had sufficient data for that variable. RESULTS: Searches identified 4223 articles of which 18 studies were included with a total 44 patients undergoing cardiac surgery. Within these studies, 12 (66.7%) reported populations undergoing coronary artery bypass graft (CABG) surgery, three (16.7%) aortic valve replacements (AVR) and three (16.7%) aortic dissection repairs. Overall mean postoperative length of ICU stay was 3.39 (95% confidence interval (CI): 0.38, 6.39) and mean postoperative length of hospital stay was 17.88 (95% CI: 14.57, 21.19). CONCLUSION: This systematic review and meta‐analysis investigated studies of limited quality which characterized cardiac surgery in COVID‐19 positive patients and demonstrates that these patients have poor outcomes. Further issues to be explored are effects of COVID‐19 on decision‐making in cardiac surgery, and effects of COVID‐19 on the cardiovascular system at a cellular level.
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spelling pubmed-91114662022-05-17 Cardiac surgery on patients with COVID‐19: a systematic review and meta‐analysis Gupta, Aashray K. Leslie, Alasdair Hewitt, Joseph N. Kovoor, Joshua G. Ovenden, Christopher D. Edwards, Suzanne Chan, Justin C. Y. Worthington, Michael G. ANZ J Surg Review Articles INTRODUCTION: The COVID‐19 pandemic has had a significant impact on global surgery. In particular, deleterious effects of SARS‐CoV‐2 infection on the heart and cardiovascular system have been described. To inform surgical patients, we performed a systematic review and meta‐analysis aiming to characterize outcomes of COVID‐19 positive patients undergoing cardiac surgery. METHODS: The study protocol was registered with PROSPERO (CRD42021228533) and conformed with PRISMA 2020 and MOOSE guidelines. PubMed, Ovid MEDLINE and Web of Science were searched between 1 January 2019 to 24 February 2022 for studies reporting outcomes on COVID‐19 positive patients undergoing cardiac surgery. Study screening, data extraction and risk of bias assessment were conducted in duplicate. Meta‐analysis was conducted using a random‐effects model where at least two studies had sufficient data for that variable. RESULTS: Searches identified 4223 articles of which 18 studies were included with a total 44 patients undergoing cardiac surgery. Within these studies, 12 (66.7%) reported populations undergoing coronary artery bypass graft (CABG) surgery, three (16.7%) aortic valve replacements (AVR) and three (16.7%) aortic dissection repairs. Overall mean postoperative length of ICU stay was 3.39 (95% confidence interval (CI): 0.38, 6.39) and mean postoperative length of hospital stay was 17.88 (95% CI: 14.57, 21.19). CONCLUSION: This systematic review and meta‐analysis investigated studies of limited quality which characterized cardiac surgery in COVID‐19 positive patients and demonstrates that these patients have poor outcomes. Further issues to be explored are effects of COVID‐19 on decision‐making in cardiac surgery, and effects of COVID‐19 on the cardiovascular system at a cellular level. John Wiley & Sons Australia, Ltd 2022-04-03 2022-05 /pmc/articles/PMC9111466/ /pubmed/35373439 http://dx.doi.org/10.1111/ans.17667 Text en © 2022 The Authors. ANZ Journal of Surgery published by John Wiley & Sons Australia, Ltd on behalf of Royal Australasian College of Surgeons. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Articles
Gupta, Aashray K.
Leslie, Alasdair
Hewitt, Joseph N.
Kovoor, Joshua G.
Ovenden, Christopher D.
Edwards, Suzanne
Chan, Justin C. Y.
Worthington, Michael G.
Cardiac surgery on patients with COVID‐19: a systematic review and meta‐analysis
title Cardiac surgery on patients with COVID‐19: a systematic review and meta‐analysis
title_full Cardiac surgery on patients with COVID‐19: a systematic review and meta‐analysis
title_fullStr Cardiac surgery on patients with COVID‐19: a systematic review and meta‐analysis
title_full_unstemmed Cardiac surgery on patients with COVID‐19: a systematic review and meta‐analysis
title_short Cardiac surgery on patients with COVID‐19: a systematic review and meta‐analysis
title_sort cardiac surgery on patients with covid‐19: a systematic review and meta‐analysis
topic Review Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9111466/
https://www.ncbi.nlm.nih.gov/pubmed/35373439
http://dx.doi.org/10.1111/ans.17667
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