Cargando…

Vaccine based on folded RBD‐PreS fusion protein with potential to induce sterilizing immunity to SARS‐CoV‐2 variants

BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is responsible for the ongoing global COVID‐19 pandemic. One possibility to control the pandemic is to induce sterilizing immunity through the induction and maintenance of neutralizing antibodies preventing SARS‐CoV‐2 from ente...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gattinger, Pia, Kratzer, Bernhard, Tulaeva, Inna, Niespodziana, Katarzyna, Ohradanova‐Repic, Anna, Gebetsberger, Laura, Borochova, Kristina, Garner‐Spitzer, Erika, Trapin, Doris, Hofer, Gerhard, Keller, Walter, Baumgartner, Isabella, Tancevski, Ivan, Khaitov, Musa, Karaulov, Alexander, Stockinger, Hannes, Wiedermann, Ursula, Pickl, Winfried F., Valenta, Rudolf
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9111473/ https://www.ncbi.nlm.nih.gov/pubmed/35357709 http://dx.doi.org/10.1111/all.15305

Ejemplares similares

Omicron: A SARS‐CoV‐2 variant of real concern
por: Gattinger, Pia, et al.
Publicado: (2022)

Antibodies in serum of convalescent patients following mild COVID‐19 do not always prevent virus‐receptor binding
por: Gattinger, Pia, et al.
Publicado: (2020)

Preventive Allergen-Specific Vaccination Against Allergy: Mission Possible?
por: Tulaeva, Inna, et al.
Publicado: (2020)

Neutralization of SARS‐CoV‐2 requires antibodies against conformational receptor‐binding domain epitopes
por: Gattinger, Pia, et al.
Publicado: (2021)

Importance, Applications and Features of Assays Measuring SARS-CoV-2 Neutralizing Antibodies
por: Gattinger, Pia, et al.
Publicado: (2023)

SARS-CoV-2-mRNA Booster Vaccination Reverses Non-Responsiveness and Early Antibody Waning in Immunocompromised Patients – A Phase Four Study Comparing Immune Responses in Patients With Solid Cancers, Multiple Myeloma and Inflammatory Bowel Disease
por: Wagner, Angelika, et al.
Publicado: (2022)

Full seroconversion in initial non-responders with higher antibody levels after heterologous COVID-19 vaccination schedule.
por: Wagner, Angelika, et al.
Publicado: (2022)

Lack of Induction of RBD-Specific Neutralizing Antibodies despite Repeated Heterologous SARS-CoV-2 Vaccination Leading to Seroconversion and Establishment of T Cell-Specific Memory in a Patient in Remission of Multiple Myeloma
por: Kratzer, Bernhard, et al.
Publicado: (2022)

Dissection of Antibody Responses of Gam-COVID-Vac-Vaccinated Subjects Suggests Involvement of Epitopes Outside RBD in SARS-CoV-2 Neutralization
por: Byazrova, Maria, et al.
Publicado: (2023)

Immunological imprint of COVID‐19 on human peripheral blood leukocyte populations
por: Kratzer, Bernhard, et al.
Publicado: (2020)

Combined assessment of S‐ and N‐specific IL‐2 and IL‐13 secretion and CD69 neo‐expression for discrimination of post–infection and post‐vaccination cellular SARS‐CoV‐2‐specific immune response
por: Kratzer, Bernhard, et al.
Publicado: (2022)

SARS-CoV-2-Specific Antibody (Ab) Levels and the Kinetic of Ab Decline Determine Ab Persistence Over 1 Year
por: Garner-Spitzer, Erika, et al.
Publicado: (2022)

Past, present, and future of allergen immunotherapy vaccines
por: Dorofeeva, Yulia, et al.
Publicado: (2020)

Lower magnitude and faster waning of antibody responses to SARS-CoV-2 vaccination in anti-TNF-α-treated IBD patients are linked to lack of activation and expansion of cTfh1 cells and impaired B memory cell formation
por: Garner-Spitzer, Erika, et al.
Publicado: (2023)

Dissociation of the respiratory syncytial virus F protein-specific human IgG, IgA and IgM response
por: Borochova, Kristina, et al.
Publicado: (2021)

Time to Kill and Time to Heal: The Multifaceted Role of Lactoferrin and Lactoferricin in Host Defense
por: Ohradanova-Repic, Anna, et al.
Publicado: (2023)

Editorial: Role of Metabolism in Regulating Immune Cell Fate Decisions
por: Ohradanova-Repic, Anna, et al.
Publicado: (2020)

Quantification, epitope mapping and genotype cross-reactivity of hepatitis B preS-specific antibodies in subjects vaccinated with different dosage regimens of BM32
por: Tulaeva, Inna, et al.
Publicado: (2020)

Prevention of allergy by virus‐like nanoparticles (VNP) delivering shielded versions of major allergens in a humanized murine allergy model
por: Kratzer, Bernhard, et al.
Publicado: (2018)

Allergen alters IL‐2/αIL‐2‐based Treg expansion but not tolerance induction in an allergen‐specific mouse model
por: Köhler, Cordula, et al.
Publicado: (2020)

Blockade of TMPRSS2-mediated priming of SARS-CoV-2 by lactoferricin
por: Ohradanova-Repic, Anna, et al.
Publicado: (2022)

Differentiation of human monocytes and derived subsets of macrophages and dendritic cells by the HLDA10 monoclonal antibody panel
por: Ohradanova-Repic, Anna, et al.
Publicado: (2016)

M2 Polarization of Human Macrophages Favors Survival of the Intracellular Pathogen Chlamydia pneumoniae
por: Buchacher, Tanja, et al.
Publicado: (2015)

All the small things: How virus‐like particles and liposomes modulate allergic immune responses
por: Kratzer, Bernhard, et al.
Publicado: (2019)

Immunotherapy With the PreS-based Grass Pollen Allergy Vaccine BM32 Induces Antibody Responses Protecting Against Hepatitis B Infection
por: Cornelius, Carolin, et al.
Publicado: (2016)

Albumins represent highly cross-reactive animal allergens
por: Liu, Zicheng, et al.
Publicado: (2023)

Recombinant allergens for immunotherapy: state of the art
por: Zhernov, Yury, et al.
Publicado: (2019)

Years in Review: Recent Progress in Cellular Allergology
por: Kratzer, Bernhard, et al.
Publicado: (2016)

Cumulative IgE-levels specific for respiratory allergens as biomarker to predict efficacy of anti-IgE-based treatment of severe asthma
por: Naumova, Veronika, et al.
Publicado: (2022)

Features of the Human Antibody Response against the Respiratory Syncytial Virus Surface Glycoprotein G
por: Borochova, Kristina, et al.
Publicado: (2020)

Molecular Approaches for Diagnosis, Therapy and Prevention of Cow’s Milk Allergy
por: Linhart, Birgit, et al.
Publicado: (2019)

Soluble pattern recognition molecules: Guardians and regulators of homeostasis at airway mucosal surfaces
por: Smole, Ursula, et al.
Publicado: (2020)

On Peptides and Altered Peptide Ligands: From Origin, Mode of Action and Design to Clinical Application (Immunotherapy)
por: Candia, Martín, et al.
Publicado: (2016)

The small molecule inhibitor BX-795 uncouples IL-2 production from inhibition of Th2 inflammation and induces CD4(+) T cells resembling iTreg
por: Tauber, Peter A., et al.
Publicado: (2023)

Genetic restriction of antigen-presentation dictates allergic sensitization and disease in humanized mice
por: Neunkirchner, Alina, et al.
Publicado: (2018)

IgG4 drives M2a macrophages to a regulatory M2b‐like phenotype: potential implication in immune tolerance
por: Bianchini, Rodolfo, et al.
Publicado: (2018)

Next-Generation of Allergen-Specific Immunotherapies: Molecular Approaches
por: Curin, Mirela, et al.
Publicado: (2018)

CD8(+) T Cell Fate and Function Influenced by Antigen-Specific Virus-Like Nanoparticles Co-Expressing Membrane Tethered IL-2
por: Wojta-Stremayr, Daniela, et al.
Publicado: (2015)

The mannose 6‐phosphate/insulin‐like growth factor 2 receptor mediates plasminogen‐induced efferocytosis
por: Ohradanova‐Repic, Anna, et al.
Publicado: (2019)

Microarray-Based Allergy Diagnosis: Quo Vadis?
por: Huang, Huey-Jy, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_d2u50eefkhk4qfii6q2flj6kof