Cargando…
Nucleoside analogues for the treatment of animal trypanosomiasis
Animal trypanosomiasis (AT) is a parasitic disease with high socio-economic impact. Given the limited therapeutic options and problems of toxicity and drug resistance, this study assessed redirecting our previously identified antitrypanosomal nucleosides for the treatment of AT. Promising hits were...
Autores principales: | Mabille, Dorien, Ilbeigi, Kayhan, Hendrickx, Sarah, Ungogo, Marzuq A., Hulpia, Fabian, Lin, Cai, Maes, Louis, de Koning, Harry P., Van Calenbergh, Serge, Caljon, Guy |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9111543/ https://www.ncbi.nlm.nih.gov/pubmed/35567803 http://dx.doi.org/10.1016/j.ijpddr.2022.05.001 |
Ejemplares similares
-
4E Interacting Protein as a Potential Novel Drug Target for Nucleoside Analogues in Trypanosoma brucei
por: Mabille, Dorien, et al.
Publicado: (2021) -
6-Methyl-7-deazapurine nucleoside analogues as broad-spectrum antikinetoplastid agents
por: Lin, Cai, et al.
Publicado: (2021) -
Cloning and Characterization of Trypanosoma congolense and T. vivax Nucleoside Transporters Reveal the Potential of P1-Type Carriers for the Discovery of Broad-Spectrum Nucleoside-Based Therapeutics against Animal African Trypanosomiasis
por: Ungogo, Marzuq A., et al.
Publicado: (2023) -
Combining tubercidin and cordycepin scaffolds results in highly active candidates to treat late-stage sleeping sickness
por: Hulpia, Fabian, et al.
Publicado: (2019) -
Comparison of Bioluminescent Substrates in Natural Infection Models of Neglected Parasitic Diseases
por: Hendrickx, Sarah, et al.
Publicado: (2022)