COVID‐19 severity from Omicron and Delta SARS‐CoV‐2 variants

The Omicron variant of SARS‐CoV‐2 achieved worldwide dominance in late 2021. Early work suggests that infections caused by the Omicron variant may be less severe than those caused by the Delta variant. We sought to compare clinical outcomes of infections caused by these two strains, confirmed by who...

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Detalles Bibliográficos
Autores principales: Wrenn, Jesse O., Pakala, Suman B., Vestal, Grant, Shilts, Meghan H., Brown, Hunter M., Bowen, Sara M., Strickland, Britton A., Williams, Timothy, Mallal, Simon A., Jones, Ian D., Schmitz, Jonathan E., Self, Wesley H., Das, Suman R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Short Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9111734/
https://www.ncbi.nlm.nih.gov/pubmed/35415869
http://dx.doi.org/10.1111/irv.12982
Descripción
Sumario:The Omicron variant of SARS‐CoV‐2 achieved worldwide dominance in late 2021. Early work suggests that infections caused by the Omicron variant may be less severe than those caused by the Delta variant. We sought to compare clinical outcomes of infections caused by these two strains, confirmed by whole genome sequencing, over a short period of time, from respiratory samples collected from SARS‐CoV‐2 positive patients at a large medical center. We found that infections caused by the Omicron variant caused significantly less morbidity, including admission to the hospital and requirement for oxygen supplementation, and significantly less mortality than those caused by the Delta variant.

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