Cargando…
HDAC Inhibition as Potential Therapeutic Strategy to Restore the Deregulated Immune Response in Severe COVID-19
The COVID-19 pandemic has had a devastating impact worldwide and has been a great challenge for the scientific community. Vaccines against SARS-CoV-2 are now efficiently lessening COVID-19 mortality, although finding a cure for this infection is still a priority. An unbalanced immune response and th...
Autores principales: | Ripamonti, Chiara, Spadotto, Valeria, Pozzi, Pietro, Stevenazzi, Andrea, Vergani, Barbara, Marchini, Mattia, Sandrone, Giovanni, Bonetti, Emanuele, Mazzarella, Luca, Minucci, Saverio, Steinkühler, Christian, Fossati, Gianluca |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9111747/ https://www.ncbi.nlm.nih.gov/pubmed/35592335 http://dx.doi.org/10.3389/fimmu.2022.841716 |
Ejemplares similares
-
The Importance of the “Time Factor” for the Evaluation of Inhibition Mechanisms: The Case of Selected HDAC6 Inhibitors
por: Cellupica, Edoardo, et al.
Publicado: (2023) -
Difluoromethyl-1,3,4-oxadiazoles are slow-binding substrate analog inhibitors of histone deacetylase 6 with unprecedented isotype selectivity
por: Cellupica, Edoardo, et al.
Publicado: (2022) -
Identification of a Novel SSTR3 Full Agonist for the Treatment of Nonfunctioning Pituitary Adenomas
por: Modena, Daniela, et al.
Publicado: (2023) -
The pan HDAC inhibitor Givinostat improves muscle function and histological parameters in two Duchenne muscular dystrophy murine models expressing different haplotypes of the LTBP4 gene
por: Licandro, Simonetta Andrea, et al.
Publicado: (2021) -
HDAC2 deregulation in tumorigenesis is causally connected to repression of immune modulation and defense escape
por: Conte, Mariarosaria, et al.
Publicado: (2014)