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Antibiotic treatment targeting gram negative bacteria prevents neratinib-induced diarrhea in rats
BACKGROUND: Neratinib is a pan-ErbB tyrosine kinase inhibitor used for extended adjuvant treatment of HER2-positive breast cancer. Diarrhea is the main adverse event associated with neratinib treatment. We aimed here to determine whether antibiotic-induced gut microbial shifts altered development of...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Neoplasia Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9111977/ https://www.ncbi.nlm.nih.gov/pubmed/35561424 http://dx.doi.org/10.1016/j.neo.2022.100806 |