Structural basis of human IL-18 sequestration by the decoy receptor IL-18 binding protein in inflammation and tumor immunity

Human Interleukin-18 (IL-18) is an omnipresent proinflammatory cytokine of the IL-1 family with central roles in autoimmune and inflammatory diseases and serves as a staple biomarker in the evaluation of inflammation in physiology and disease, including the inflammatory phase of COVID-19. The seques...

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Detalles Bibliográficos
Autores principales: Detry, Sam, Andries, Julie, Bloch, Yehudi, Gabay, Cem, Clancy, Danielle M., Savvides, Savvas N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9111989/
https://www.ncbi.nlm.nih.gov/pubmed/35398099
http://dx.doi.org/10.1016/j.jbc.2022.101908

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