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Prediction and confirmation of a switch-like region within the N-terminal domain of hSIRT1

Many proteins display conformational changes resulting from allosteric regulation. Often only a few residues are crucial in conveying these structural and functional allosteric changes. These regions that undergo a significant change in structure upon receiving an input signal, such as molecular rec...

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Detalles Bibliográficos
Autores principales:	Huynh, Angelina T., Nguyen, Thi-Tina N., Villegas, Carina A., Montemorso, Saira, Strauss, Benjamin, Pearson, Richard A., Graham, Jason G., Oribello, Jonathan, Suresh, Rohit, Lustig, Brooke, Wang, Ningkun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9112024/ https://www.ncbi.nlm.nih.gov/pubmed/35592613 http://dx.doi.org/10.1016/j.bbrep.2022.101275

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