Cargando…

Identification and Validation of Novel Biomarkers for Hepatocellular Carcinoma, Liver Fibrosis/Cirrhosis and Chronic Hepatitis B via Transcriptome Sequencing Technology

PURPOSE: The aim of this study was to identify and validate novel biomarkers for distinguishing among hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC), liver fibrosis/liver cirrhosis (LF/LC) and chronic hepatitis B (CHB). PATIENTS AND METHODS: Transcriptomic sequencing was conducted on...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhao, Dandan, Zhang, Xiaoxiao, Tang, Yuhui, Guo, Peilin, Ai, Rong, Hou, Mengmeng, Wang, Yiqi, Yuan, Xiwei, Cui, Luyao, Zhang, Yuguo, Zhao, Suxian, Li, Wencong, Wang, Yang, Sun, Xiaoye, Liu, Lingdi, Dong, Shiming, Li, Lu, Zhao, Wen, Nan, Yuemin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9112460/ https://www.ncbi.nlm.nih.gov/pubmed/35592243 http://dx.doi.org/10.2147/JHC.S357380

Ejemplares similares

Glutamate-Cysteine Ligase Catalytic Subunit Attenuated Hepatitis C Virus-Related Liver Fibrosis and Suppressed Endoplasmic Reticulum Stress
por: Fu, Na, et al.
Publicado: (2020)

LINC00886 Facilitates Hepatocellular Carcinoma Tumorigenesis by Sequestering microRNA-409-3p and microRNA-214-5p
por: Li, Lu, et al.
Publicado: (2023)

Heme oxygenase 1 alleviates nonalcoholic steatohepatitis by suppressing hepatic ferroptosis
por: Yuan, Xiwei, et al.
Publicado: (2023)

Heme Oxygenase-1 Suppresses Wnt Signaling Pathway in Nonalcoholic Steatohepatitis-Related Liver Fibrosis
por: Du, Jinghua, et al.
Publicado: (2020)

Activation of peroxisome proliferator activated receptor alpha ameliorates ethanol induced steatohepatitis in mice
por: Kong, Lingbo, et al.
Publicado: (2011)

Resveratrol ameliorates nutritional steatohepatitis through the mmu-miR-599/PXR pathway
por: Kong, Lingbo, et al.
Publicado: (2022)

Machine learning-based predictive and risk analysis using real-world data with blood biomarkers for hepatitis B patients in the malignant progression of hepatocellular carcinoma
por: Nan, Yuemin, et al.
Publicado: (2022)

MiR-146a-5p suppresses activation and proliferation of hepatic stellate cells in nonalcoholic fibrosing steatohepatitis through directly targeting Wnt1 and Wnt5a
por: Du, Jinghua, et al.
Publicado: (2015)

Geographic Distribution of HCV Genotypes and Efficacy of Direct-Acting Antivirals in Chronic HCV-Infected Patients in North and Northeast China: A Real-World Multicenter Study
por: Li, Wencong, et al.
Publicado: (2022)

MiR-130a-3p attenuates activation and induces apoptosis of hepatic stellate cells in nonalcoholic fibrosing steatohepatitis by directly targeting TGFBR1 and TGFBR2
por: Wang, Yang, et al.
Publicado: (2017)

Involvement of the Interleukin-23/Interleukin-17 Axis in Chronic Hepatitis C Virus Infection and Its Treatment Responses
por: Meng, Ping, et al.
Publicado: (2016)

Correction: Ping Meng, et al. Involvement of the Interleukin-23/Interleukin-17 Axis in Chronic Hepatitis C Virus Infection and Its Treatment Responses. Int. J. Mol. Sci. 2016, 17, 1070
por: Meng, Ping, et al.
Publicado: (2016)

Mitofusin-2 gene polymorphisms and metabolic dysfunction associated fatty liver disease: a case-control study in a Chinese population
por: Yuan, Xiwei, et al.
Publicado: (2023)

Diagnostic efficacy of noninvasive liver fibrosis indexes in predicting portal hypertension in patients with cirrhosis
por: Wang, Le, et al.
Publicado: (2017)

Consensus on the tertiary prevention of primary liver cancer
por: Nan, Yuemin, et al.
Publicado: (2023)

Coffee Consumption Decreases Risks for Hepatic Fibrosis and Cirrhosis: A Meta-Analysis
por: Liu, Fen, et al.
Publicado: (2015)

Correlation between CT features and liver function and p53 expression in hepatitis, cirrhosis and hepatocellular carcinoma
por: Hu, Yahui, et al.
Publicado: (2018)

Individual surveillance by competing risk model for patients with hepatocellular carcinoma occurrence in all-cause cirrhosis
por: Wang, Qi, et al.
Publicado: (2023)

Hyperactive Follicular Helper T Cells Contribute to Dysregulated Humoral Immunity in Patients With Liver Cirrhosis
por: Zhao, Juanjuan, et al.
Publicado: (2019)

Serum Liver Fibrosis Markers in the Prognosis of Liver Cirrhosis: A Prospective Observational Study
por: Qi, Xingshun, et al.
Publicado: (2016)

Serum liver fibrosis markers predict hepatic decompensation in compensated cirrhosis
por: Chen, Qingling, et al.
Publicado: (2023)

Efficacy and Safety of Emricasan in Liver Cirrhosis and/or Fibrosis
por: Mu, Li-ya, et al.
Publicado: (2021)

Heme oxygenase-1 prevents non-alcoholic steatohepatitis through suppressing hepatocyte apoptosis in mice
por: Nan, YueMin, et al.
Publicado: (2010)

Diabetes Mellitus and Risk of Hepatic Fibrosis/Cirrhosis
por: Li, Xu, et al.
Publicado: (2019)

Comparison of Electrocardiogram and QT Interval between Viral Hepatitis Cirrhosis and Alcoholic Cirrhosis
por: Lu, Li-Hong, et al.
Publicado: (2022)

Nomogram for predicting advanced liver fibrosis and cirrhosis in patients with chronic liver disease
por: Ding, Rongrong, et al.
Publicado: (2021)

FibroBox: a novel noninvasive tool for predicting significant liver fibrosis and cirrhosis in HBV infected patients
por: Lu, Xiao-Jie, et al.
Publicado: (2020)

Serum Zonulin in HBV-Associated Chronic Hepatitis, Liver Cirrhosis, and Hepatocellular Carcinoma
por: Wang, Xin, et al.
Publicado: (2019)

Safety, efficacy and prognosis of anticoagulant therapy for portal vein thrombosis in cirrhosis: a retrospective cohort study
por: Zhang, Zhiqi, et al.
Publicado: (2023)

Genomics and proteomics in liver fibrosis and cirrhosis
por: Hannivoort, Rebekka A, et al.
Publicado: (2012)

A Note on the Fibrosis of Hepatic Cirrhosis
por: Rolleston, H. D.
Publicado: (1897)

Complement 5a is an indicator of significant fibrosis and earlier cirrhosis in patients chronically infected with hepatitis B virus
por: Deng, Yongqiong, et al.
Publicado: (2016)

FXYD6 overexpression in HBV-related hepatocellular carcinoma with cirrhosis
por: Chen, Xiongfei, et al.
Publicado: (2020)

Transient Elastography and Ultrasonography: Optimal Evaluation of Liver Fibrosis and Cirrhosis in Patients with Chronic Hepatitis B Concurrent with Nonalcoholic Fatty Liver Disease
por: Zhang, Geng-lin, et al.
Publicado: (2019)

The role of exosomes in hepatitis, liver cirrhosis and hepatocellular carcinoma
por: Shen, Jiliang, et al.
Publicado: (2017)

Metabolic defects in splenic B cell compartments from patients with liver cirrhosis
por: Huang, Man, et al.
Publicado: (2020)

Novel index for the prediction of significant liver fibrosis and cirrhosis in chronic hepatitis B patients in China
por: Liao, Min-Jun, et al.
Publicado: (2022)

Histopathological evaluation of liver fibrosis and cirrhosis regression
por: Lo, Regina C., et al.
Publicado: (2017)

A review of liver fibrosis and cirrhosis regression
por: Lee, Michael J.
Publicado: (2023)

Clinical Characteristics of Systemic Lupus Erythematosus with Cirrhosis
por: You, Hanxiao, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_8dbb30c3kuachcl2e1pi4nndg1