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Machine learning approach informs biology of cancer drug response

BACKGROUND: The mechanism of action for most cancer drugs is not clear. Large-scale pharmacogenomic cancer cell line datasets offer a rich resource to obtain this knowledge. Here, we present an analysis strategy for revealing biological pathways that contribute to drug response using publicly availa...

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Detalles Bibliográficos
Autores principales: Zhu, Eliot Y., Dupuy, Adam J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9112473/
https://www.ncbi.nlm.nih.gov/pubmed/35581546
http://dx.doi.org/10.1186/s12859-022-04720-z