Glucagon-like peptide-1 attenuates diabetes-associated osteoporosis in ZDF rat, possibly through the RAGE pathway

BACKGROUND: Diabetes-associated osteoporosis are partly caused by accumulation of advanced glycation endproducts (AGEs). Glucagon-like peptide-1 (GLP-1) has been shown to regulate bone turnover. Here we explore whether GLP-1 receptor agonist (GLP1RA) can have a beneficial effect on bone in diabetes...

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Detalles Bibliográficos
Autores principales: Cheng, Yanzhen, Liu, Peng, Xiang, Qianru, Liang, Jiamin, Chen, Huafeng, Zhang, Hua, Yang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9112483/
https://www.ncbi.nlm.nih.gov/pubmed/35581617
http://dx.doi.org/10.1186/s12891-022-05396-5

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