Folic acid intervention during pregnancy alters DNA methylation, affecting neural target genes through two distinct mechanisms

BACKGROUND: We previously showed that continued folic acid (FA) supplementation beyond the first trimester of pregnancy appears to have beneficial effects on neurocognitive performance in children followed for up to 11 years, but the biological mechanism for this effect has remained unclear. Using s...

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Detalles Bibliográficos
Autores principales: Ondičová, Miroslava, Irwin, Rachelle E., Thursby, Sara-Jayne, Hilman, Luke, Caffrey, Aoife, Cassidy, Tony, McLaughlin, Marian, Lees-Murdock, Diane J., Ward, Mary, Murphy, Michelle, Lamers, Yvonne, Pentieva, Kristina, McNulty, Helene, Walsh, Colum P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9112484/
https://www.ncbi.nlm.nih.gov/pubmed/35578268
http://dx.doi.org/10.1186/s13148-022-01282-y

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