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MTHFD2 is a potential oncogene for its strong association with poor prognosis and high level of immune infiltrates in urothelial carcinomas of bladder

BACKGROUND: The bifunctional methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase (MTHFD2) has been reported to play an oncogenic role in various types of cancers. However, the function of MTHFD2 in urothelial carcinomas of bladder (UCB) and its associ...

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Detalles Bibliográficos
Autores principales: Zhu, Lin, Liu, Xianhui, Zhang, Weiyu, Hu, Hao, Wang, Qi, Xu, Kexin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9112551/
https://www.ncbi.nlm.nih.gov/pubmed/35581573
http://dx.doi.org/10.1186/s12885-022-09606-0