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An Electrostatically-steered Conformational Selection Mechanism Promotes SARS-CoV-2 Spike Protein Variation

After two years since the outbreak, the COVID-19 pandemic remains a global public health emergency. SARS-CoV-2 variants with substitutions on the spike (S) protein emerge increasing the risk of immune evasion and cross-species transmission. Here, we analyzed the evolution of the S protein as recorde...

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Detalles Bibliográficos
Autores principales:	Sorokina, Marija, Belapure, Jaydeep, Tüting, Christian, Paschke, Reinhard, Papasotiriou, Ioannis, Rodrigues, João P.G.L.M., Kastritis, Panagiotis L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Author(s). Published by Elsevier Ltd. 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9112565/ https://www.ncbi.nlm.nih.gov/pubmed/35595165 http://dx.doi.org/10.1016/j.jmb.2022.167637

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