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Characterization of early and late transition states of the folding pathway of a SH2 domain

Albeit SH2 domains are abundant protein–protein interaction modules with fundamental roles in the regulation of several physiological and molecular pathways in the cell, the available information about the determinants of their thermodynamic stability and folding properties are still very limited. I...

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Detalles Bibliográficos
Autores principales: Toto, Angelo, Malagrinò, Francesca, Nardella, Caterina, Pennacchietti, Valeria, Pagano, Livia, Santorelli, Daniele, Diop, Awa, Gianni, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9112803/
https://www.ncbi.nlm.nih.gov/pubmed/35634781
http://dx.doi.org/10.1002/pro.4332