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Monitoring Recovery After Pediatric ACL Reconstruction Utilizing Promis

INTRODUCTION: Anterior Cruciate Ligament Reconstruction (ACL-R) is increasingly common procedure performed in pediatric and adolescents. Patient-Reported Outcomes Measurements Information System (PROMIS) computer adaptive testing (CAT) has demonstrated to be a valid and reliable means to assess PROs...

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Autores principales: Block, Andrew M., Ganapathy, Aravinda, Nepple, Jeffrey J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9112813/
http://dx.doi.org/10.1177/2325967121S00385
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author Block, Andrew M.
Ganapathy, Aravinda
Nepple, Jeffrey J.
author_facet Block, Andrew M.
Ganapathy, Aravinda
Nepple, Jeffrey J.
author_sort Block, Andrew M.
collection PubMed
description INTRODUCTION: Anterior Cruciate Ligament Reconstruction (ACL-R) is increasingly common procedure performed in pediatric and adolescents. Patient-Reported Outcomes Measurements Information System (PROMIS) computer adaptive testing (CAT) has demonstrated to be a valid and reliable means to assess PROs in the pediatric population. Currently, all studies looking at the performance of PROMIS in the ACL-R population have utilized adult cohorts. PURPOSE: To characterize the recovery after pediatric ACL-R utilizing PROMIS including (1) changes in PROMIS domains during 1-year postoperative period and (2) to investigate if PROMIS scores can identify patients with early signs of arthrofibrosis at 6 weeks postoperatively and deficits in return to play testing at 6 months. METHODS: Pediatric patients that underwent ACL-R were prospectively assessed with PROMIS at each clinical visit. PROMIS CAT domains included Mobility and Pain Interference. Inclusion criteria included patients <18 years old who underwent ACL-R with both pre-operative and >6 month PROMIS scores. Time points were as followed: baseline, 1 week, 1 month, 3 months, 6 months, and 1 year. Time points were compared utilizing a mixed-linear regression model. Significance was set at p<0.05. Early signs of arthrofibrosis were identified at 6 weeks postoperatively and defined as flexion less than 90° and lack of full extension greater than 5° regarding best values at physical therapy visits and/or office physical exam. Return to play was assessed via hop testing at 6 months postoperatively with deficits defined as greater than 10% compared to contralateral. RESULTS: The study included 62 ACL-R with a mean age of 14.6±1.9 years. Patients demonstrated significant increases in Mobility and Pain Interference compared to pre-operative values by 3 months postoperatively and continued to significantly improve through 6 months (Figure 1 and 2). Significant improvements from 6 months to 1 year were not seen in either domain (all p>0.05). At 6 weeks postoperatively, 24% of patients had signs of early arthrofibrosis (none ultimately requiring surgical intervention). Significant differences in PROMIS Mobility (29.1 v. 35.1, p=0.001) were present between patients with and without early arthrofibrosis, while differences in Pain Interference were not significant (53.0 vs. 49.4, p=0.15). Patients with deficits on hop testing at return to play had lower PROMIS mobility (48.2 vs. 54.4, p=0.04) and higher PROMIS pain interference (38.9 vs. 33.8, p=0.02) than without deficits. CONCLUSIONS: PROMIS domains are easily obtained and demonstrate utility in monitoring pediatric patients after ACL-R including early signs of arthrofibrosis and deficits at return to play testing.
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spelling pubmed-91128132022-05-18 Monitoring Recovery After Pediatric ACL Reconstruction Utilizing Promis Block, Andrew M. Ganapathy, Aravinda Nepple, Jeffrey J. Orthop J Sports Med Article INTRODUCTION: Anterior Cruciate Ligament Reconstruction (ACL-R) is increasingly common procedure performed in pediatric and adolescents. Patient-Reported Outcomes Measurements Information System (PROMIS) computer adaptive testing (CAT) has demonstrated to be a valid and reliable means to assess PROs in the pediatric population. Currently, all studies looking at the performance of PROMIS in the ACL-R population have utilized adult cohorts. PURPOSE: To characterize the recovery after pediatric ACL-R utilizing PROMIS including (1) changes in PROMIS domains during 1-year postoperative period and (2) to investigate if PROMIS scores can identify patients with early signs of arthrofibrosis at 6 weeks postoperatively and deficits in return to play testing at 6 months. METHODS: Pediatric patients that underwent ACL-R were prospectively assessed with PROMIS at each clinical visit. PROMIS CAT domains included Mobility and Pain Interference. Inclusion criteria included patients <18 years old who underwent ACL-R with both pre-operative and >6 month PROMIS scores. Time points were as followed: baseline, 1 week, 1 month, 3 months, 6 months, and 1 year. Time points were compared utilizing a mixed-linear regression model. Significance was set at p<0.05. Early signs of arthrofibrosis were identified at 6 weeks postoperatively and defined as flexion less than 90° and lack of full extension greater than 5° regarding best values at physical therapy visits and/or office physical exam. Return to play was assessed via hop testing at 6 months postoperatively with deficits defined as greater than 10% compared to contralateral. RESULTS: The study included 62 ACL-R with a mean age of 14.6±1.9 years. Patients demonstrated significant increases in Mobility and Pain Interference compared to pre-operative values by 3 months postoperatively and continued to significantly improve through 6 months (Figure 1 and 2). Significant improvements from 6 months to 1 year were not seen in either domain (all p>0.05). At 6 weeks postoperatively, 24% of patients had signs of early arthrofibrosis (none ultimately requiring surgical intervention). Significant differences in PROMIS Mobility (29.1 v. 35.1, p=0.001) were present between patients with and without early arthrofibrosis, while differences in Pain Interference were not significant (53.0 vs. 49.4, p=0.15). Patients with deficits on hop testing at return to play had lower PROMIS mobility (48.2 vs. 54.4, p=0.04) and higher PROMIS pain interference (38.9 vs. 33.8, p=0.02) than without deficits. CONCLUSIONS: PROMIS domains are easily obtained and demonstrate utility in monitoring pediatric patients after ACL-R including early signs of arthrofibrosis and deficits at return to play testing. SAGE Publications 2022-05-13 /pmc/articles/PMC9112813/ http://dx.doi.org/10.1177/2325967121S00385 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by-nc-nd/4.0/This open-access article is published and distributed under the Creative Commons Attribution - NonCommercial - No Derivatives License (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits the noncommercial use, distribution, and reproduction of the article in any medium, provided the original author and source are credited. You may not alter, transform, or build upon this article without the permission of the Author(s). For article reuse guidelines, please visit SAGE’s website at http://www.sagepub.com/journals-permissions.
spellingShingle Article
Block, Andrew M.
Ganapathy, Aravinda
Nepple, Jeffrey J.
Monitoring Recovery After Pediatric ACL Reconstruction Utilizing Promis
title Monitoring Recovery After Pediatric ACL Reconstruction Utilizing Promis
title_full Monitoring Recovery After Pediatric ACL Reconstruction Utilizing Promis
title_fullStr Monitoring Recovery After Pediatric ACL Reconstruction Utilizing Promis
title_full_unstemmed Monitoring Recovery After Pediatric ACL Reconstruction Utilizing Promis
title_short Monitoring Recovery After Pediatric ACL Reconstruction Utilizing Promis
title_sort monitoring recovery after pediatric acl reconstruction utilizing promis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9112813/
http://dx.doi.org/10.1177/2325967121S00385
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