Linker-Improved Chimeric Endolysin Selectively Kills Staphylococcus aureus In Vitro, on Reconstituted Human Epidermis, and in a Murine Model of Skin Infection

Staphylococcus aureus causes a broad spectrum of diseases in humans and animals. It is frequently associated with inflammatory skin disorders such as atopic dermatitis, where it aggravates symptoms. Treatment of S. aureus-associated skin infections with antibiotics is discouraged due to their broad-...

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Detalles Bibliográficos
Autores principales: Eichenseher, Fritz, Herpers, Bjorn L., Badoux, Paul, Leyva-Castillo, Juan M., Geha, Raif S., van der Zwart, Mathijs, McKellar, James, Janssen, Ferd, de Rooij, Bob, Selvakumar, Lavanja, Röhrig, Christian, Frieling, Johan, Offerhaus, Mark, Loessner, Martin J., Schmelcher, Mathias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9112974/
https://www.ncbi.nlm.nih.gov/pubmed/35416713
http://dx.doi.org/10.1128/aac.02273-21

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