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Exosome Mediated Cytosolic Cisplatin Delivery Through Clathrin-Independent Endocytosis and Enhanced Anti-cancer Effect via Avoiding Endosome Trapping in Cisplatin-Resistant Ovarian Cancer

BACKGROUND: Ovarian carcinoma is one of the most common gynecologic malignancies, cisplatin resistance has become a key obstacle to the successful treatment of ovarian cancer because ovarian carcinomas are liable to drug resistance. To find an effective drug carrier is an urgent need. METHODS: Exoso...

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Detalles Bibliográficos
Autores principales: Zhou, Guannan, Gu, Yuanyuan, Zhu, Zhongyi, Zhang, Hongdao, Liu, Wei, Xu, Beiying, Zhou, Fangyue, Zhang, Menglei, Hua, Keqin, Wu, Ligang, Ding, Jingxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113028/
https://www.ncbi.nlm.nih.gov/pubmed/35592860
http://dx.doi.org/10.3389/fmed.2022.810761