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Comparative Genomics Reveals Insights into the Divergent Evolution of Astigmatic Mites and Household Pest Adaptations
Highly diversified astigmatic mites comprise many medically important human household pests such as house dust mites causing ∼1–2% of all allergic diseases globally; however, their evolutionary origin and diverse lifestyles including reversible parasitism have not been illustrated at the genomic lev...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113151/ https://www.ncbi.nlm.nih.gov/pubmed/35535514 http://dx.doi.org/10.1093/molbev/msac097 |
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author | Xiong, Qing Wan, Angel Tsz-Yau Liu, Xiaoyu Fung, Cathy Sin-Hang Xiao, Xiaojun Malainual, Nat Hou, Jinpao Wang, Lingyi Wang, Mingqiang Yang, Kevin Yi Cui, Yubao Leung, Elaine Lai-Han Nong, Wenyan Shin, Soo-Kyung Au, Shannon Wing-Ngor Jeong, Kyoung Yong Chew, Fook-Tim Hui, Jerome Ho-Lam Leung, Ting-Fan Tungtrongchitr, Anchalee Zhong, Nanshan Liu, Zhigang Tsui, Stephen Kwok-Wing |
author_facet | Xiong, Qing Wan, Angel Tsz-Yau Liu, Xiaoyu Fung, Cathy Sin-Hang Xiao, Xiaojun Malainual, Nat Hou, Jinpao Wang, Lingyi Wang, Mingqiang Yang, Kevin Yi Cui, Yubao Leung, Elaine Lai-Han Nong, Wenyan Shin, Soo-Kyung Au, Shannon Wing-Ngor Jeong, Kyoung Yong Chew, Fook-Tim Hui, Jerome Ho-Lam Leung, Ting-Fan Tungtrongchitr, Anchalee Zhong, Nanshan Liu, Zhigang Tsui, Stephen Kwok-Wing |
author_sort | Xiong, Qing |
collection | PubMed |
description | Highly diversified astigmatic mites comprise many medically important human household pests such as house dust mites causing ∼1–2% of all allergic diseases globally; however, their evolutionary origin and diverse lifestyles including reversible parasitism have not been illustrated at the genomic level, which hampers allergy prevention and our exploration of these household pests. Using six high-quality assembled and annotated genomes, this study not only refuted the monophyly of mites and ticks, but also thoroughly explored the divergence of Acariformes and the diversification of astigmatic mites. In monophyletic Acariformes, Prostigmata known as notorious plant pests first evolved, and then rapidly evolving Astigmata diverged from soil oribatid mites. Within astigmatic mites, a wide range of gene families rapidly expanded via tandem gene duplications, including ionotropic glutamate receptors, triacylglycerol lipases, serine proteases and UDP glucuronosyltransferases. Gene diversification after tandem duplications provides many genetic resources for adaptation to sensing environmental signals, digestion, and detoxification in rapidly changing household environments. Many gene decay events only occurred in the skin-burrowing parasitic mite Sarcoptes scabiei. Throughout the evolution of Acariformes, massive horizontal gene transfer events occurred in gene families such as UDP glucuronosyltransferases and several important fungal cell wall lytic enzymes, which enable detoxification and digestive functions and provide perfect drug targets for pest control. This comparative study sheds light on the divergent evolution and quick adaptation to human household environments of astigmatic mites and provides insights into the genetic adaptations and even control of human household pests. |
format | Online Article Text |
id | pubmed-9113151 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-91131512022-05-18 Comparative Genomics Reveals Insights into the Divergent Evolution of Astigmatic Mites and Household Pest Adaptations Xiong, Qing Wan, Angel Tsz-Yau Liu, Xiaoyu Fung, Cathy Sin-Hang Xiao, Xiaojun Malainual, Nat Hou, Jinpao Wang, Lingyi Wang, Mingqiang Yang, Kevin Yi Cui, Yubao Leung, Elaine Lai-Han Nong, Wenyan Shin, Soo-Kyung Au, Shannon Wing-Ngor Jeong, Kyoung Yong Chew, Fook-Tim Hui, Jerome Ho-Lam Leung, Ting-Fan Tungtrongchitr, Anchalee Zhong, Nanshan Liu, Zhigang Tsui, Stephen Kwok-Wing Mol Biol Evol Discoveries Highly diversified astigmatic mites comprise many medically important human household pests such as house dust mites causing ∼1–2% of all allergic diseases globally; however, their evolutionary origin and diverse lifestyles including reversible parasitism have not been illustrated at the genomic level, which hampers allergy prevention and our exploration of these household pests. Using six high-quality assembled and annotated genomes, this study not only refuted the monophyly of mites and ticks, but also thoroughly explored the divergence of Acariformes and the diversification of astigmatic mites. In monophyletic Acariformes, Prostigmata known as notorious plant pests first evolved, and then rapidly evolving Astigmata diverged from soil oribatid mites. Within astigmatic mites, a wide range of gene families rapidly expanded via tandem gene duplications, including ionotropic glutamate receptors, triacylglycerol lipases, serine proteases and UDP glucuronosyltransferases. Gene diversification after tandem duplications provides many genetic resources for adaptation to sensing environmental signals, digestion, and detoxification in rapidly changing household environments. Many gene decay events only occurred in the skin-burrowing parasitic mite Sarcoptes scabiei. Throughout the evolution of Acariformes, massive horizontal gene transfer events occurred in gene families such as UDP glucuronosyltransferases and several important fungal cell wall lytic enzymes, which enable detoxification and digestive functions and provide perfect drug targets for pest control. This comparative study sheds light on the divergent evolution and quick adaptation to human household environments of astigmatic mites and provides insights into the genetic adaptations and even control of human household pests. Oxford University Press 2022-05-10 /pmc/articles/PMC9113151/ /pubmed/35535514 http://dx.doi.org/10.1093/molbev/msac097 Text en © The Author(s) 2022. Published by Oxford University Press on behalf of Society for Molecular Biology and Evolution. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Discoveries Xiong, Qing Wan, Angel Tsz-Yau Liu, Xiaoyu Fung, Cathy Sin-Hang Xiao, Xiaojun Malainual, Nat Hou, Jinpao Wang, Lingyi Wang, Mingqiang Yang, Kevin Yi Cui, Yubao Leung, Elaine Lai-Han Nong, Wenyan Shin, Soo-Kyung Au, Shannon Wing-Ngor Jeong, Kyoung Yong Chew, Fook-Tim Hui, Jerome Ho-Lam Leung, Ting-Fan Tungtrongchitr, Anchalee Zhong, Nanshan Liu, Zhigang Tsui, Stephen Kwok-Wing Comparative Genomics Reveals Insights into the Divergent Evolution of Astigmatic Mites and Household Pest Adaptations |
title | Comparative Genomics Reveals Insights into the Divergent Evolution of Astigmatic Mites and Household Pest Adaptations |
title_full | Comparative Genomics Reveals Insights into the Divergent Evolution of Astigmatic Mites and Household Pest Adaptations |
title_fullStr | Comparative Genomics Reveals Insights into the Divergent Evolution of Astigmatic Mites and Household Pest Adaptations |
title_full_unstemmed | Comparative Genomics Reveals Insights into the Divergent Evolution of Astigmatic Mites and Household Pest Adaptations |
title_short | Comparative Genomics Reveals Insights into the Divergent Evolution of Astigmatic Mites and Household Pest Adaptations |
title_sort | comparative genomics reveals insights into the divergent evolution of astigmatic mites and household pest adaptations |
topic | Discoveries |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113151/ https://www.ncbi.nlm.nih.gov/pubmed/35535514 http://dx.doi.org/10.1093/molbev/msac097 |
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