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LGL1 binds to Integrin β1 and inhibits downstream signaling to promote epithelial branching in the mammary gland
Branching morphogenesis is a fundamental process by which organs in invertebrates and vertebrates form branches to expand their surface areas. The current dogma holds that directional cell migration determines where a new branch forms and thus patterns branching. Here, we asked whether mouse Lgl1, a...
Autores principales: | Ma, Rongze, Gong, Difei, You, Huanyang, Xu, Chongshen, Lu, Yunzhe, Bergers, Gabriele, Werb, Zena, Klein, Ophir D., Petritsch, Claudia K., Lu, Pengfei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113222/ https://www.ncbi.nlm.nih.gov/pubmed/35172155 http://dx.doi.org/10.1016/j.celrep.2022.110375 |
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