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Synergistic antibacterial photocatalytic and photothermal properties over bowl-shaped TiO(2) nanostructures on Ti-19Zr-10Nb-1Fe alloy
As implant substitutes are increasingly applied to the clinic, the infection caused by implants has become one of the most common complications, and the modification of the antibacterial function of the implant can reduce such complications. In this work, a well-defined bowl-shaped nanostructure coa...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113230/ https://www.ncbi.nlm.nih.gov/pubmed/35592141 http://dx.doi.org/10.1093/rb/rbac025 |
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author | Wu, Yan Deng, Zichao Wang, Xueying Chen, Aihua Li, Yan |
author_facet | Wu, Yan Deng, Zichao Wang, Xueying Chen, Aihua Li, Yan |
author_sort | Wu, Yan |
collection | PubMed |
description | As implant substitutes are increasingly applied to the clinic, the infection caused by implants has become one of the most common complications, and the modification of the antibacterial function of the implant can reduce such complications. In this work, a well-defined bowl-shaped nanostructure coating with photocatalytic and photothermal synergistic antibacterial properties was prepared on Ti-19Zr-10Nb-1Fe (TZNF) alloy. The coating is obtained by spin-coating and sintering TiO(2) precursors templated from self-assembled microspheres of polystyrene-poly(4-vinylpyridine) (PS-P4VP) amphiphilic block polymer on TZNF alloy. PS-P4VP provides the bowl-shaped TiO(2) nanostructures doped with C, N elements, reducing the band-gap of TiO(2), which can absorb near-infrared (NIR) light to release reactive oxygen species and produce photothermal conversion. The bowl structure is expected to enhance the utilization of light via the reflection in the confined space. The bowl-shaped surface has 100% antibacterial rates after 30 min of NIR light irradiation. In addition to antibacterial properties, the bowl-shaped surface has better hydrophilicity and protein adsorption capacity. The amount of protein adsorbed on TZNF with the bowl-shaped structures was six times that of TZNF. Hence, the bowl-shaped nanostructure can promote the proliferation and adhesion of osteoblasts, the cell proliferation rate was increased by 10–30%. |
format | Online Article Text |
id | pubmed-9113230 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-91132302022-05-18 Synergistic antibacterial photocatalytic and photothermal properties over bowl-shaped TiO(2) nanostructures on Ti-19Zr-10Nb-1Fe alloy Wu, Yan Deng, Zichao Wang, Xueying Chen, Aihua Li, Yan Regen Biomater Research Article As implant substitutes are increasingly applied to the clinic, the infection caused by implants has become one of the most common complications, and the modification of the antibacterial function of the implant can reduce such complications. In this work, a well-defined bowl-shaped nanostructure coating with photocatalytic and photothermal synergistic antibacterial properties was prepared on Ti-19Zr-10Nb-1Fe (TZNF) alloy. The coating is obtained by spin-coating and sintering TiO(2) precursors templated from self-assembled microspheres of polystyrene-poly(4-vinylpyridine) (PS-P4VP) amphiphilic block polymer on TZNF alloy. PS-P4VP provides the bowl-shaped TiO(2) nanostructures doped with C, N elements, reducing the band-gap of TiO(2), which can absorb near-infrared (NIR) light to release reactive oxygen species and produce photothermal conversion. The bowl structure is expected to enhance the utilization of light via the reflection in the confined space. The bowl-shaped surface has 100% antibacterial rates after 30 min of NIR light irradiation. In addition to antibacterial properties, the bowl-shaped surface has better hydrophilicity and protein adsorption capacity. The amount of protein adsorbed on TZNF with the bowl-shaped structures was six times that of TZNF. Hence, the bowl-shaped nanostructure can promote the proliferation and adhesion of osteoblasts, the cell proliferation rate was increased by 10–30%. Oxford University Press 2022-05-04 /pmc/articles/PMC9113230/ /pubmed/35592141 http://dx.doi.org/10.1093/rb/rbac025 Text en © The Author(s) 2022. Published by Oxford University Press. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Wu, Yan Deng, Zichao Wang, Xueying Chen, Aihua Li, Yan Synergistic antibacterial photocatalytic and photothermal properties over bowl-shaped TiO(2) nanostructures on Ti-19Zr-10Nb-1Fe alloy |
title | Synergistic antibacterial photocatalytic and photothermal properties over bowl-shaped TiO(2) nanostructures on Ti-19Zr-10Nb-1Fe alloy |
title_full | Synergistic antibacterial photocatalytic and photothermal properties over bowl-shaped TiO(2) nanostructures on Ti-19Zr-10Nb-1Fe alloy |
title_fullStr | Synergistic antibacterial photocatalytic and photothermal properties over bowl-shaped TiO(2) nanostructures on Ti-19Zr-10Nb-1Fe alloy |
title_full_unstemmed | Synergistic antibacterial photocatalytic and photothermal properties over bowl-shaped TiO(2) nanostructures on Ti-19Zr-10Nb-1Fe alloy |
title_short | Synergistic antibacterial photocatalytic and photothermal properties over bowl-shaped TiO(2) nanostructures on Ti-19Zr-10Nb-1Fe alloy |
title_sort | synergistic antibacterial photocatalytic and photothermal properties over bowl-shaped tio(2) nanostructures on ti-19zr-10nb-1fe alloy |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9113230/ https://www.ncbi.nlm.nih.gov/pubmed/35592141 http://dx.doi.org/10.1093/rb/rbac025 |
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